Informace o publikaci

Changes in Hematologic and Coagulation Profiles in Rabbits with Right-ventricle Pacing

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UHRIKOVA Ivana SEPŠI Milan HLOZKOVA Jana SUCHY Pavel KASAJOVA Marta MACHACKOVA Katerina DELEV Delian P. CICCOCIOPPO Rachele KRUZLIAK Peter SCHEER Peter

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Folia Medica
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1515/folmed-2016-0013
Obor Farmakologie a lékárnická chemie
Klíčová slova aPTT; activated partial thromboplastin time; FDP-fibrin degradation products
Popis Objectives: The aim of this study was to evaluate changes in hematology and coagulation in rabbits with right-ventricle pacing without medication. Animals and methods: Blood was collected from ten non-anesthetized male rabbits from the jugular vein before and one month after pacemaker placement. Total erythrocyte, leukocyte and platelet count, hemoglobin, hematocrit and diff erential leukocyte count were done on automatic veterinary flow cytometry hematologic analyzer. Prothrombin time, activated partial thromboplastin time, fibrinogen level, D-dimers and kaolin-activated thromboelastography was measured from citrated blood.Results: We found an increase in red blood cell mass and decrease in platelet count, while coagulation tests did not diff er between samplings.

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