Informace o publikaci
Impulse control disorders in patients with young-onset Parkinson's disease: A cross-sectional study seeking associated factors
| Autoři | |
|---|---|
| Rok publikování | 2016 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Basal Ganglia |
| Fakulta / Pracoviště MU | |
| Citace | |
| Doi | http://dx.doi.org/10.1016/j.baga.2016.09.001 |
| Obor | Neurologie, neurochirurgie, neurovědy |
| Klíčová slova | Parkinson's disease; Impulse control disorders; Pathological gambling; Dopamine agonists; Personality |
| Přiložené soubory | |
| Popis | Introduction: The aim of this cross-sectional study was to investigate the frequency and factors associated with impulse control disorder (ICD) symptoms, including personality characteristics, in Czech young-onset Parkinson's disease (PD) patients. Subjects and methods: We examined 49 young-onset PD patients and 38 age-matched control subjects. ICD symptoms were identified using the South Oaks Gambling Screen and modified Minnesota Impulse Disorders Interview. Results: A higher prevalence of pathological gambling and hypersexuality was found in PD patients than in control subjects. A higher frequency of pathological gambling in our sample of young-onset PD patients was found in patients using dopamine agonists and in patients with dyskinesias lasting 5 or more years. The frequency of any ICD symptom was associated with coffee consumption, higher reported anxiety, and somatization. ICD symptoms were also related to personality characteristics in PD patients; specifically, patients who manifested any ICD symptom scored significantly higher on Self-assertive/ Antisocial and Reserved/Schizoid personality styles and pathological gambling was associated with lower reported Conscientiousness. Conclusion: Our results demonstrate that ICD presents a real problem in young-onset PD patients. Knowledge about the factors associated with ICD symptoms might be helpful in the proactive search for these pathological behaviours in this specific subgroup of PD patients. |
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