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The effect of type 2 diabetes on selected clinical parameters and disease outcome in patients with colorectal cancer

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PÁCAL Lukáš VALÍK Dalibor MALÚŠKOVÁ Denisa JARKOVSKÝ Jiří KLIKA Petr OBERMANNOVÁ Radka DUŠEK Ladislav KAŇKOVÁ Kateřina

Rok publikování 2017
Druh Konferenční abstrakty
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Popis Recent epidemiological evidence indicates increased incidence of certain cancer types in patients with type 2 diabetes mellitus (T2DM), worse outcomes and also certain modifying effect of various glucose-lowering therapies. Given the population prevalence of both T2DM and colorectal cancer (CRC) their relationship is particularly relevant. Study objective was to analyse tumour-, patient- and treatment-related characteristics explaining possible difference in selected outcomes between CRC subjects with and without pre-existing diabetes by means of in-depth epidemiological analysis of all consecutive patients diagnosed and treated for CRC over the past 10 years (stratified by the presence/absence of T2DM) in the largest cancer centre in Czech Republic - Masaryk Memorial Cancer Institute (MMCI) in Brno.
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