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Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

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STAŠKOVÁ Klára TOUŠEK Pavel TOUŠEK František MALÁ Anna ŽELÍZKO Michael HORÁK David SLUKA Martin VODZINSKÁ Alexandra JANČAR Radek ASCHERMANN Michael JARKOVSKÝ Jiří WIDIMSKÝ Petr

Rok publikování 2018
Druh Článek v odborném periodiku
Časopis / Zdroj Cor et Vasa
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1016/j.crvasa.2017.02.007
Klíčová slova Elderly; Acute coronary syndrome; Treatment strategy; Outcome
Popis Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +/- 4 and 82.1 +/- 5 years (p < 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p < 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.

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