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Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene
Autoři | |
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Rok publikování | 2018 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Materials Letters |
Fakulta / Pracoviště MU | |
Citace | |
www | https://www.sciencedirect.com/science/article/pii/S0167577X18309297?via%3Dihub |
Doi | http://dx.doi.org/10.1016/j.matlet.2018.06.023 |
Klíčová slova | Phosphazene; Amino; Electrospinning; Biomaterials; Biomimetic; Morphology |
Popis | Here we report for the first time that blending hexaamino-cyclo-triphosphazene with either poly-epsilon-caprolactone or poly-L-lactic acid enables the generation of blended electrospun scaffolds with enhanced bioactivities. These hexaamino-cyclo-triphosphazene-modified fibers significantly promote cell adhesion, spreading, metabolism, and proliferation. In addition to that we also report more efficient hexaaminocyclo-triphosphazene synthesis with a higher yield and purity. |
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