
Efficacy of new cephalosporins in treatment of multidrug-resistant strains of gram-negative bacteria in burn patients
Autoři | |
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Rok publikování | 2019 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Burns |
Fakulta / Pracoviště MU | |
Citace | |
www | http://dx.doi.org/10.1016/j.burns.2019.06.005 |
Doi | http://dx.doi.org/10.1016/j.burns.2019.06.005 |
Klíčová slova | multidrug-resistant strains; gram-negative bacteria; cephalosporins |
Popis | Burn patients are confronted with a variety of potentiallypathogenic microorganisms every day. Although increasingprevalence of micromycetal infections has been observed,especially in the last decade, bacteria remain the dominantpathogens in the etiology of infectious complications in thesepatients. In particular, gram-negative bacteria have a signifi-cant impact on mortality and morbidity of burn patients(Enterobacteriaceae, Pseudomonas aeruginosa). One possibleexplanation is a dramatic increase in resistance of thesepathogens (high prevalence of multidrug resistant–MDR–bacterial strains) and the second possibility is an insufficientamount of available and effective antibiotics (especiallyagainst carbapenem-resistantEnterobacteriaceae—CRE). |