The EurOPDX Data Portal: an open platform for patient-derived cancer xenograft data sharing and visualization

• Autoři: DUDOVÁ Zdenka; CONTE Nathalie; MASON Jeremy; STUCHLÍK Dalibor; PEŠA Radim; HALMAGYI Csaba; PEROVA Zinaida; MOSAKU Abayomi; THORNE Ross; FOLLETTE Alex; PIVARČ Ľuboslav; ŠAŠINKA Radim; USMAN Muhammad; NEUHAUSER Steven; BEGLEY Dale A; KRUPKE Debra M; FRASSA Massimiliano; FIORI Alessandro; CORSI Riccardo; VEZZADINI Luca; ISELLA Claudio; BERTOTTI Andrea; BULT Carol; PARKINSON Helen; MEDICO Enzo; MEEHAN Terrence; KŘENEK Aleš
• Rok publikování: 2022
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: BMC Genomics
• Fakulta / Pracoviště MU: Ústav výpočetní techniky
• www: https://doi.org/10.1186/s12864-022-08367-1
• Doi: http://dx.doi.org/10.1186/s12864-022-08367-1
• Klíčová slova: PDX Molecular data analysis; Data harmonization; Research infrastructure; Database
• Popis: Patient-derived xenografts (PDX) mice models play an important role in preclinical trials and personalized medicine. Sharing data on the models is highly valuable for numerous reasons – ethical, economical, research cross validation etc. The EurOPDX Consortium was established 8 years ago to share such information and avoid duplicating efforts in developing new PDX mice models and unify approaches to support preclinical research. EurOPDX Data Portal is the unified data sharing platform adopted by the Consortium.