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大腸癌の診断方法
Autoři | |
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Rok publikování | 2021 |
Druh | Patent |
Fakulta / Pracoviště MU | |
Vydavatel | |
Číslo patentu | JP6989863B2 |
www | Espacenet |
Popis | The present invention relates to a method for diagnosing colorectal cancer and a method for predicting prognosis. In this method, piRNA-hsa-5937 (sequence: TCCCTGGTGGTCTAGTGGTTAGGATTCGGCA (SEQ ID NO: 1)), miR-23a-3p (sequence: AUCACAUUGCCAGGGAUUUCC (SEQ ID NO: 3)), miR-27a-3p (sequence: UUCACAGUGGCUAAGUUCCGC (SEQ ID NO: 4)). )) And one or more miRNAs selected from miR-142-5p (SEQ ID NO: CAUAAAGUAGAAAGCACUACU (SEQ ID NO: 5)) are used as biomarkers. The resulting method uses body fluid as input. Therefore, this method is non-invasive, has high sensitivity and specificity even in the earliest stages of the disease, and is cost-effective. |
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