Informace o publikaci
How alternative splicing changes the properties of plant proteins
| Autoři | |
|---|---|
| Rok publikování | 2022 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Quantitative Plant Biology |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://www.cambridge.org/core/journals/quantitative-plant-biology/article/how-alternative-splicing-changes-the-properties-of-plant-proteins/D683880A361185F3A55ABDEC421809BB |
| Doi | http://dx.doi.org/10.1017/qpb.2022.9 |
| Klíčová slova | alternative splicing; competitive inhibition; feedback loop; network motifs; plant development; RNA processing. |
| Popis | Most plant primary transcripts undergo alternative splicing (AS), and its impact on protein diversity is a subject of intensive investigation. Several studies have uncovered various mechanisms of how particular protein splice isoforms operate. However, the common principles behind the AS effects on protein function in plants have rarely been surveyed. Here, on the selected examples, we highlight diverse tissue expression patterns, subcellular localization, enzymatic activities, abilities to bind other molecules and other relevant features. We describe how the protein isoforms mutually interact to underline their intriguing roles in altering the functionality of protein complexes. Moreover, we also discuss the known cases when these interactions have been placed inside the autoregulatory loops. This review is particularly intended for plant cell and developmental biologists who would like to gain inspiration on how the splice variants encoded by their genes of interest may coordinately work. |