Informace o publikaci
Oral microbiota in patients with oral squamous cell carcinoma
| Autoři | |
|---|---|
| Rok publikování | 2022 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Oral squamous cell carcinoma (OSCC) is the most common malignancy in the head and neck region and, despite advances in treatment, is often diagnosed only at a late stage and has a poor prognosis. Oral carcinogenesis is a multifactorial process involving the effect of the exposome and subsequent cytogenetic and epigenetic changes in keratinocytes. External risk factors include tobacco, alcohol abuse, and malhygiene, which can affect the composition of the oral microbiota. 1 Oral microbiota (bacteriome, mycobiome, and virome) has been associated with oral cancer through a wide range of mechanisms2 , but the relationship has not been thoroughly characterized. |
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