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OverProt: secondary structure consensus for protein families

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MIDLIK Adam HUTAŘOVÁ VAŘEKOVÁ Ivana HUTAŘ Jan CHARESHNEU Aliaksei BERKA Karel SVOBODOVÁ Radka

Rok publikování 2022
Druh Článek v odborném periodiku
Časopis / Zdroj Bioinformatics
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www https://academic.oup.com/bioinformatics/article/38/14/3648/6604272
Doi http://dx.doi.org/10.1093/bioinformatics/btac384
Klíčová slova protein family; OverProt
Popis Every protein family has a set of characteristic secondary structures. However, due to individual variations, a single structure is not enough to represent the whole family. OverProt can create a secondary structure consensus, showing the general fold of the family as well as its variation. Our server provides precomputed results for all CATH superfamilies and user-defined computations, visualized by an interactive viewer, which shows the secondary structure element type, length, frequency of occurrence, spatial variability and beta-connectivity.
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