Informace o publikaci
Common xanthene fluorescent dyes are visible-light activatable CO-releasing molecules
| Autoři | |
|---|---|
| Rok publikování | 2023 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Organic and Biomolecular Chemistry |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB01823C |
| Doi | http://dx.doi.org/10.1039/d2ob01823c |
| Klíčová slova | CARBON-MONOXIDE; QUANTUM YIELD; EOSIN-Y; PHOTOCHEMISTRY; OXYGEN; PHOTODEGRADATION; ANGIOGRAPHY; MECHANISM |
| Popis | Fluorescein, eosin Y, and rose bengal are dyes used in clinical medicine and considered (photo-)chemically stable. Upon extensive irradiation with visible light in aqueous solutions, we found that these compounds release carbon monoxide (CO) - a bioactive gasotransmitter - in 40-100% yields along with the production of low-mass secondary photoproducts, such as phthalic and formic acids, in a multistep degradation process. Such photochemistry should be considered in applications of these dyes, and they could also be utilized as visible-light activatable CO-releasing molecules (photoCORMs) with biological implications. |
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