Informace o publikaci
Brain metabolic derangements examined using 1H MRS and their (in)consistency among different rodent models of depression
Název česky | Metabolické změny mozku zkoumané pomocí 1H MRS a jejich (ne)konzistence mezi různými modely deprese u hlodavců |
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Autoři | |
Rok publikování | 2023 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY |
Fakulta / Pracoviště MU | |
Citace | |
www | https://www.sciencedirect.com/science/article/pii/S0278584623000945?via%3Dihub |
Doi | http://dx.doi.org/10.1016/j.pnpbp.2023.110808 |
Klíčová slova | Animal models Depression Proton magnetic resonance spectroscopy Metabolites |
Přiložené soubory | |
Popis | This review summarises the current knowledge of 1H MRS findings from rodent models of MDD, assesses the results from both a biological and a technical perspective, and identifies the main sources of bias. From a technical point of view, bias-introducing factors are the diversity of the measured volumes and their positioning in the brain, the data processing, and the metabolite concentration expression. |
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