Informace o publikaci

Optimized target delineation procedure for the radiosurgery treatment of ventricular tachycardia: observer-independent accuracy

Autoři	HECKO Jan KNYBEL Lukas RYBAR Marian PENHAKER Marek JIRAVSKÝ Otakar NEUWIRTH Radek SRAMKO Marek HASKOVA Jana KAUTZNER Josef CVEK Jakub
Rok publikování	2024
Druh	Článek v odborném periodiku
Časopis / Zdroj	Reports of Practical Oncology and Radiotherapy
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
www	https://journals.viamedica.pl/rpor/article/view/100387
Doi	http://dx.doi.org/10.5603/rpor.100387
Klíčová slova	ventricular tachycardia; radioablation; target delineation; intraobserver; interobserver
Popis	Background: Part of the current stereotactic arrythmia radioablation (STAR) workflow is transfer of findings from the electroanatomic mapping (EAM) to computed tomography (CT). Here, we analyzed inter- and intraobserver variation in a modified EAM-CT registration using automatic registration algorithms designed to yield higher robustness. Materials and methods: This work is based on data of 10 patients who had previously undergone STAR. Two observers participated in this study: (1) an electrophysiologist technician (cardiology) with substatial experience in EAM-CT merge, and (2) a clinical engineer (radiotherapy) with minimum experience with EAM-CT merge. EAM-CT merge consists of 3 main steps: segmentation of left ventricle from CT (CT LV), registration of the CT LV and EAM, clinical target volume (CTV) delineation from EAM specific points. Mean Hausdorff distance (MHD), Dice Similarity Coefficient (DSC) and absolute difference in Center of Gravity (CoG) were used to assess intra/interobserver variability. Results: Intraobserver variability: The mean DSC and MHD for 3 CT LVs altogether was 0.92 +/- 0.01 and 1.49 +/- 0.23 mm. The mean DSC and MHD for 3 CTVs altogether was 0,82 +/- 0,06 and 0,71 +/- 0,22 mm. Interobserver variability: Segmented CT LVs showed great similarity (mean DSC of 0,91 +/- 0,01, MHD of 1,86 +/- 0,47 mm). The mean DSC comparing CTVs from both observers was 0,81 +/- 0,11 and MHD was 0,87 +/- 0,45 mm. Conclusions: The high interobserver similarity of segmented LVs and delineated CTVs confirmed the robustness of the proposed method. Even an inexperienced user can perform a precise EAM-CT merge following workflow instructions.