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Analysis of very-high frequency phenomena in human brain slices measured using microelectrode arrays (MEA)
Autoři | |
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Rok publikování | 2024 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | |
Popis | It is hypothesized that very high-frequency oscillations (500–2000 Hz) detected by intracerebral macroelectrodes may represent the summated activity of different neuronal subgroups that exhibit different asynchronous firing rates and phases. In recent years, multielectrode arrays (MEAs) have emerged as a powerful tool for recording electrical activity from human brain slices, providing valuable insights into the underlying mechanisms of epilepsy. The objective of our study was to perform spatiotemporal clustering of extracellular action potentials (EAPs) to contribute to the understanding of the mechanisms of VHFO generation. |
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