Informace o publikaci
High-Resolution Imaging of Transient RNA Polymerase II Biomolecular Condensates
| Autoři | |
|---|---|
| Rok publikování | 2024 |
| Druh | Další prezentace na konferencích |
| Fakulta / Pracoviště MU | |
| Citace | |
| Přiložené soubory | |
| Popis | Biomolecular condensates, which assemble in cells to regulate key biological processes, are challenging to study due to their inherently dynamic nature. In this talk, we will present our integrative multi-scale approach, which integrates light microscopy, electron cryomicroscopy, cryotomography, and coarse-grained simulations. Together, these methods reveal new insights into the molecular organization and biogenesis of a model RNA polymerase II condensate, shedding light on its structural complexity. |