Informace o publikaci
Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering
| Autoři | |
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| Rok publikování | 2024 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | International Journal of Biological Macromolecules |
| Fakulta / Pracoviště MU | |
| Citace | KORÁBKOVÁ, Eva, Zhanna BOEVA, Katarzyna Anna RADASZKIEWICZ, Kateřina SKOPALOVÁ, Věra KAŠPÁRKOVÁ, Wenyang XU, Xiaoju WANG, Jiří PACHERNÍK, Antonín MINAŘÍK, Tom LINDFORS a Petr HUMPOLÍČEK. Stimuli-responsive thin film composites of conducting polymers and cellulose nanocrystals for tissue engineering. International Journal of Biological Macromolecules. Elsevier, 2024, roč. 265, April, s. 1-10. ISSN 0141-8130. Dostupné z: https://dx.doi.org/10.1016/j.ijbiomac.2024.131036. |
| www | https://doi.org/10.1016/j.ijbiomac.2024.131036 |
| Doi | http://dx.doi.org/10.1016/j.ijbiomac.2024.131036 |
| Klíčová slova | Cellulose nanocrystals; Polypyrrole; Poly(3.4-ethylenedioxythiophene); Human induced pluripotent stem cells |
| Popis | Thin composite films comprising two primary representatives of conducting polymers, poly(3, 4-ethylenedioxythiophene) (PEDOT) and polypyrrole (PPy), with eco-friendly cellulose nanocrystals (CNC) were prepared through electrochemical polymerization. The combination of CNC and PEDOT (or PPy) results in the formation of films with highly different surface topography and thickness. Intriguingly, different surface conductivity of PEDOT and PPy was revealed by atomic force microscopy albeit that the electrochemical properties were rather similar. The biological properties of the composites in contact with prospective human induced pluripotent stem cells (hiPSC) and cardiomyocytes derived from hiPSC demonstrated good cytocompatibility of both composites and their potential in engineering of electro-sensitive tissues. The as-prepared conducting, eco-friendly and cytocompatible composites are thus promising candidates for biomedical applications where stimuli-responsivity is a crucial cell-instructive property. |
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