Informace o publikaci

Microwave Application in 1,3-Dipolar Cycloadditions and Their Influence upon Formation of either 1,3-Oxazolidines or Pyrrolidines

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POTÁČEK Milan

Rok publikování 2000
Druh Článek ve sborníku
Konference Proceedings - International Conference on Microwave Chemistry
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
Obor Organická chemie
Popis A way to preparation of ethyl-N-alkyl-3,4-disubstituted pyrrolidine-2-carboxylates by the reaction of azomethine ylide and dipolarophile under microwave irradiation was searched. The ylide was generated in situ by the reaction of ethyl-N-alkylaminoacetates with paraformaldehyde. Fumaronitrile and dimethylfumarate were used as dipolarophiles. Comparison of reaction in toluene and under solventless conditions as well as influence of a solid support was searched.
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