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Informace o publikaci
Microwave Application in 1,3-Dipolar Cycloadditions and Their Influence upon Formation of either 1,3-Oxazolidines or Pyrrolidines
Autoři | |
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Rok publikování | 2000 |
Druh | Článek ve sborníku |
Konference | Proceedings - International Conference on Microwave Chemistry |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Organická chemie |
Popis | A way to preparation of ethyl-N-alkyl-3,4-disubstituted pyrrolidine-2-carboxylates by the reaction of azomethine ylide and dipolarophile under microwave irradiation was searched. The ylide was generated in situ by the reaction of ethyl-N-alkylaminoacetates with paraformaldehyde. Fumaronitrile and dimethylfumarate were used as dipolarophiles. Comparison of reaction in toluene and under solventless conditions as well as influence of a solid support was searched. |
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