![Důležité termíny](https://cdn.muni.cz/media/3633704/image_2.jpg?mode=crop¢er=0.5,0.5&rnd=133572412150000000&heightratio=0.5&width=278)
Informace o publikaci
Activation of p53 protein to sequence-specific DNA binding by its phosphorylation
Název česky | Aktivace proteinu p53 a sekvencne-specificka DNA vazba jeho fosforylaci |
---|---|
Autoři | |
Rok publikování | 2001 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | European Journal of Biochemistry |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Onkologie a hematologie |
Popis | Protein p53 seems to be one of the most important tummor suppressor proteins. The DNA binding function is cryptic and can be activated by different stimuli modulating C-terminal domain. The most likely physiological mechanism of p53 activation is posttranslational modification, mainly phosphorylation of specific sites. |
Související projekty: |