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Accumulation of iodide in rat thyroid and skin is reduced by high bromide intake
Autoři | |
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Rok publikování | 2001 |
Druh | Článek ve sborníku |
Konference | Industrial Toxicology '2001 (Romančík V., ed.) [IF=n.a.] |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Fyziologie |
Klíčová slova | bromide; iodine; rat; thyroid |
Popis | As we have shown previously that high levels of bromide in the organism of the rat significantly influenced the extent of accumulation of iodide in the thyroid and also its elimination from the body, we intended to find out whether similar influences on the transport processes could occur also in the skin. The kinetics and extent of iodide uptake and elimination by the skin were found to be markedly influenced by a high bromide intake both under conditions of sufficient iodine supply and, even more profoundly, under conditions of iodine deficiency. |
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