Informace o publikaci
Computer modelling of effect of transversal tubules on excitation - contraction coupling in cardiac cells (Basic study)
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek ve sborníku |
| Konference | Engineering Mechanics 2001 |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Biofyzika |
| Klíčová slova | cardiac cell; T-system; quantitative modelling |
| Popis | The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the physio-logical significance of T-system in excitation-contraction coupling quantitatively. |
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