Informace o publikaci
NOVEL APPROACH TOWARDS THE OPTIMIZATION OF ORGANIC SYNTHESES USING EXPERIMENTAL DESIGN
| Autoři | |
|---|---|
| Rok publikování | 2002 |
| Druh | Článek ve sborníku |
| Fakulta / Pracoviště MU | |
| Citace | |
| Klíčová slova | criss cross cycloaddition |
| Popis | Synthesis of desired organic molecule might be complicated and usually consists of several steps. Even in case the product (intermediate) can be obtained via "single step synthesis" the optimisation might be tedious and difficult as the reaction mechanism can consist of several steps and be quite complex. Determination of reaction mechanism is usually quite a difficult task. Therefore, in this work a new approach consisted of a combination of (i) experiments designed according to a suitable Experimental Design (ED) and (ii) modelling with Artificial Neural Network (ANN) is examined and experimentally proved. |