Informace o publikaci
VYUŽITIE ZVIERACIEHO MODELU DEPRESIE PRI OVEROVANÍ ANTIDEPRESÍVNYCH ÚČINKOV FELBAMÁTU
| Autoři | |
|---|---|
| Rok publikování | 2003 |
| Druh | Článek ve sborníku |
| Konference | Abstrakta 47. Studentské vědecké konference |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | felbamate - animal model - antidepressant - olfactory bulbectomy |
| Popis | Repeated administration of felbamate (240 mg/kg/day) elicited a significant inhibition of the motor hyperactivity in the rat model of depression (Olfactory Bulbectomy Model), which indicates a potential antidepressant felbamate effects. At the same time, the significantly suppressed leukocyte phagocytosis recorded in bulbectomized rats was disinhibited by felbamate treatment. |
| Související projekty: |