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Informace o publikaci
Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats
Autoři | |
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Rok publikování | 2003 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | European Neuropsychopharmacology |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Farmakologie a lékárnická chemie |
Klíčová slova | 5-HT1 and 5-HT2 receptor ligands; methamphetamine; self-administration;rats |
Popis | Present work brings new aspects into the understanding of methamphetamine addiction studying the role of two different serotonergic receptor subtypes 5-HT1 and 5-HT2. According to our results, the most important inhibitory influence for the conditioned reward responding to methamphetamine i.v. self-administration showed pharmacological agonistic manipulation of the 5-HT1B receptor subtype. |
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