Publication details

Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats

Authors

NOVÁKOVÁ Jana

Year of publication 2003
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords 5-HT1 and 5-HT2 receptor ligands; methamphetamine; self-administration;rats
Description Present work brings new aspects into the understanding of methamphetamine addiction studying the role of two different serotonergic receptor subtypes 5-HT1 and 5-HT2. According to our results, the most important inhibitory influence for the conditioned reward responding to methamphetamine i.v. self-administration showed pharmacological agonistic manipulation of the 5-HT1B receptor subtype.
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