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Informace o publikaci
Induction by retinoids of the activity of type III-deiodinase responsible for thyroid hormone degradation in astrocytes
Autoři | |
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Rok publikování | 1994 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Cell Biology International [IF=0.884 (1993)] |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Neurologie, neurochirurgie, neurovědy |
Klíčová slova | Astrocytes; brain; deiodinase; retinoic acid; thyroid hormones |
Popis | The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-retinoic acid (RA) caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. |