Publication details
Induction by retinoids of the activity of type III-deiodinase responsible for thyroid hormone degradation in astrocytes
| Authors | |
|---|---|
| Year of publication | 1994 |
| Type | Article in Periodical |
| Magazine / Source | Cell Biology International [IF=0.884 (1993)] |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | Astrocytes; brain; deiodinase; retinoic acid; thyroid hormones |
| Description | The effects of retinoids on type III deiodinase (D-III) activity were examined in astroglial cells cultured in a chemically defined medium devoid of hormones and growth factors. Incubation of astroglial cells with 5 micromolar all-trans-retinoic acid (RA) caused up to 200-fold increase in D-III activity, which reached a plateau after 48 h. |