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Informace o publikaci
Methamphetamine behavioural senistization in rodents: interactions with selected drugs and gender.
Autoři | |
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Rok publikování | 2008 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Adiktologie |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Farmakologie a lékárnická chemie |
Klíčová slova | methamphetamine; MDMA; morphine |
Popis | Different behavioural rodent models (rat i.v. drug self-administration, mouse agonistic behaviour, open field test,) were used. Behavioural sensitization to metamphetamine was ocnfirmed after repeated pretreatment with methpahetmaine itself but also after MDMA, morphine and cannabinoid CB1 receptor agonist. A higher rewarding effect of methamphetamine was noted in the sensitized animals with estrus-like conditions and attenuated by estrogen deprivation. |
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