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Colicin E1 production is associated with bacteriocin multiproducer strains in uropathogenic Escherichia coli.

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ŠMAJS David MICENKOVÁ Lenka ŠMARDA Jan VRBA M. ŠEVČÍKOVÁ A. VALIŠOVÁ Zuzana WOZNICOVÁ Vladana

Rok publikování 2009
Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Popis The incidence of 29 bacteriocin types were tested in a group of 377 E. coli strains isolated from urinary tract infections (UTI) and in 413 control strains isolated from feces of patients without bacterial gut infection. The spectrum and frequency of individual bacteriocin types in the UTI strains was very similar to the control strains, probably reflecting the origin of UTI strains in the human gut. In the group of E. coli UTI strains, 159 bacteriocin producing strains (42.2%) were identified being not significantly different from 199 bacteriocin producers in the control group (48.2%). Producers with 3 and more identified bacteriocin types were more frequent in the UTI group. In the UTI strains, there is a marked increase of strains producing colicin E1 when compared to control (14.3% and 6.8%, respectively, p = 0.002). Moreover, this tendency is associated with multiproducers. There is a tendency in the UTI strains to possess additional genetic determinants and to synthesize colicin E1.
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