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Timely Implementation of PTA in Diabetic Patients with Defects in the Leg
Autoři | |
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Rok publikování | 2010 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | |
Popis | Aim: Compared to patiens with diabetic angiopathy by the time the implementation of endovascular interventions. Metod: 59 patients with diabetes II. type with affected tibial arteries with 1 stable defect in the legs (region MTP) or toes. Group A, 33 patients with duration of the defect on average 14 +- 2 weeks, and group B, 26 patients with defects existing 6 +- 1 week. Patiens were performed PTA on tibial arteries with stenosis. The average carried 4.2 +-1.6 dilation on 1,9 +- 0,9 arteries. Patients with closures arteries were not included in the file. Patiens had sustained dual antiplatelet therapy (ASA 100 mg / day and clopidogrel 75 mg /day or ticlopidine 400 mg / day). Results: 9-12 months after PTA were cured or diminished (> 75%) defects in 13 patients (39%) group A and in 19 patients (73%) in Group B, (p< 0.05). Virtual flow in the distal parts of the tibial arteries after PTA in both groups improved similarly increased by about averages 19.5 +- 8.9 ml / min (n.s.) Peripheral vascular reactivity appeared to trend towards improvement in group B, otherwise the groups did not differ. Group A vs. Group B 29.9 +-19.1 v. 49.1 + -19.5 PU (p< 0.05) HbA 1c in the PTA group did not differ and amounted to 8.1 +- 2.2%. After 9 to 12 months the values were in group A 8.0 + -1,9% and in group B 7.8 + -1,5% (ns). In 5 patients in Group A were within 6 months after the intervention for the deterioration and the development of other defects on the leg performed surgical revascularisation procedures. Conclusion: Earlier implementation of PTA, group B, at the same podology care had higher probability of healing defects. |