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Determination of asialotransferrin in the cerebrospinal fluid with the HPLC method
Autoři | |
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Rok publikování | 2010 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Scandiavian Journal of Clinical & Laboratory Investigation |
Fakulta / Pracoviště MU | |
Citace | |
Doi | http://dx.doi.org/10.3109/00365510903521559 |
Obor | Traumatologie a ortopedie |
Klíčová slova | Asialotransferrin; cerebrospinal fluid; HPLC; mass spectrometry |
Popis | Identification of the content of asialotransferrin in the cerebrospinal fluid is a diagnostic method for childhood-onset ataxia and central nervous system hypomyelination (CACH), also known as vanishing white matter disease (VWM), and also for other types of CNS disorders. Methods: In our work, we have determined the value of the ratio of the asialo form of transferrin to the total transferrin in the CSF using the commercially used Variant |