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Free light chain ratio as a marker of complete remission

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RADOCHA J MAISNAR Vladimír ZAHRADOVÁ Lenka HÁJEK R MACHÁLKOVÁ K VÁVROVÁ J TICHY M MALY J

Rok publikování 2011
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Popis Stringent complete remission (sCR) in multiple myeloma (MM) has been defined as complete remission (CR) with normal free light chain ratio (FLCr). However only a few studies have so far incorporated FLCr as the marker of the outcome in MM patients. Aim: Goal was to evaluate CR patients and compare the relapse rate in the group with normal FLCr and abnormal FLCr. Conclusion: So far only a few relapses occured, however it seems that in both groups the relapse rate seems to be the same regardless of FLCr status. Further longer follow-up is needed to confirm the significance of FLCr. Standardisation of methods used for FLCr evaluation is needed if we are to incorporate FLCr as a standard of CR evaluation.
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