Interleukin-1 gene variations in post-orthodontic external root resorption

• Autoři: LINHARTOVÁ Petra; ČERNOCHOVÁ Pavlína; RAUDENSKÁ Martina; LIPKOVÁ Jolana; IZAKOVIČOVÁ HOLLÁ Lydie
• Rok publikování: 2011
• Druh: Konferenční abstrakty
• Fakulta / Pracoviště MU: Lékařská fakulta
• Popis: External apical root resorption (EARR) is a permanent shortening of the end of the tooth root. EARR is a common clinical complication of orthodontic treatment and is known to occur after trauma and in response to inflammation. Polymorphisms in the interleukin-1 (IL-1) genes play a role in the inflammatory diseases through the modulation of cytokine levels. The aim of this study was to associate two single nucleotide polymorphisms (SNPs) and one variable number of tandem repeats (VNTR) polymorphism in IL-1 with EARR in the Czech population. This study was supported by projects 1M0528 and IGA NT11405-6.

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