Mgr. Michal Šmída, Dr. rer. nat.

2025

• Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode

  MARTÍN MOYANO Paula KUBINA Tadeáš PARUCH Štěpán Owen JAROŠKOVÁ Aneta NOVOTNÝ Jan SKOČKOVÁ Veronika OVESNÁ Petra SUCHÁNKOVÁ Tereza PROKOFEVA Polina KUSTER Bernhard ŠMÍDA Michal CHAIKUAD Apirat KRÄMER Andreas KNAPP Stefan SOUČEK Karel PARUCH Kamil

  Article in Periodical

  Angewandte Chemie International Edition, year: 2025, volume: 64, edition: 1, DOI

2024

• A novel thrombocytopenia-4-causing CYCS gene variant decreases caspase activity: Three-generation study

  ŠTIKA Jiří PEŠOVÁ Michaela STAŇO KOZUBÍK Kateřina SKALNÍKOVÁ Magdalena DOSTÁLOVÁ Lenka LOJA Tomáš RADOVÁ Lenka PALUŠOVÁ Veronika RÉBLOVÁ Kamila VRZALOVÁ Zuzana BLAHÁKOVÁ Ivona TRIZULJAK Jakub ULDRIJAN Stjepan BLATNÝ Jan ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

  Article in Periodical

  British journal of haematology, year: 2024, volume: 205, edition: 6, DOI

• ANALYSIS OF ALTERNATIVE THERAPEUTIC OPTIONS FOR ACUTE MYELOID LEUKEMIA PATIENTS RESISTANT TO VENETOCLAX BASED ON DRUG SCREENING AND EXPRESSION PROFILING

  STYLIANOU Filio LADUNGOVÁ Adriana HÝL Jan BUŠA Daniel ČULEN Martin WEINBERGEROVÁ Barbora MAYER Jiří ŠMÍDA Michal

  Conference abstract

  Year: 2024, type: Conference abstract

• CD20 expression regulates CD37 levels in B-cell lymphoma - implications for immunotherapies

  BOBROWICZ Malgorzata KUSOWSKA Aleksandra KRAWCZYK Marta ZHYLKO Andriy FORCADOS Christopher SLUSARCZYK Aleksander BARANKIEWICZ Joanna DOMAGALA Joanna KUBACZ Matylda ŠMÍDA Michal DOSTALOVÁ KOPEČNÁ Lenka MARHELAVA Katsiaryna FIDYT Klaudyna PEPEK Monika BARANOWSKA Iwona SZUMERA-CIECKIEWICZ Anna INDERBERG Else Marit WALCHLI Sebastien GRANICA Monika GRACZYK-JARZYNKA Agnieszka MAJCHRZAK Martyna POREBA Marcin GEHLERT Carina Lynn PEIPP Matthias FIRCZUK Malgorzata PROCHOREC-SOBIESZEK Monika WINIARSKA Magdalena

  Article in Periodical

  Oncoimmunology, year: 2024, volume: 13, edition: 1, DOI

• EXPLORING VENETOCLAX RESISTANCE MECHANISMS IN AML CELLS THROUGH GENOME-WIDE CRISPR SCREENS AND DRUG PROFILING

  LADUNGOVÁ Adriana STYLIANOU Filio PESCHELOVÁ Helena LODHI Yusuf DOSTÁLOVÁ Lenka GOTTUMUKKALA Narendra Varma ŠMÍDA Michal

  Conference abstract

  Year: 2024, type: Conference abstract

• Novel casein kinase 1 alpha inhibitors for the treatment of resistant AML and solid tumors

  JANOVSKÁ Pavlína RADASZKIEWICZ Tomasz Witold PROCHAZKOVA P PRIŠTICOVÁ Ingrid PLEŠINGEROVÁ Hana ČULEN Martin ŠMÍDA Michal BUŠA Daniel LADUNGOVÁ Adriana MAIER Lukáš HAVEL Štěpán MAYER Jiří SCHEER A PARUCH Kamil BRYJA Vítězslav

  Conference abstract

  Year: 2024, type: Conference abstract

2023

• CRISPR/Cas9 technology as a useful tool in the study of chornic lymphocytic leukemia.

  PESCHELOVÁ Helena MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• CRISPR/Cas9 technology as a useful tool in the study of chronic lymphocytic leukemia.

  PESCHELOVÁ Helena KOZLOVÁ Veronika MANČÍKOVÁ Veronika DOSTÁLOVÁ Lenka LADUNGOVÁ Adriana ŠKRNOVÁ Dominika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract

• Efficacy of CD19-directed CAR-T cells against CLL and the possibilities for its further improvements.

  ŠMÍDA Michal

  Requested lectures

  Year: 2023, type: Requested lectures

• Exploring the mechanisms of Venetoclax resistence via drug screening and genome-wide CRISPR screening.

  LADUNGOVÁ Adriana PESCHELOVÁ Helena DOSTÁLOVÁ Lenka LODHI Yusuf GOTTUMUKKALA Narendra Varma MAYER Jiří ŠMÍDA Michal

  Conference abstract

  Year: 2023, type: Conference abstract