RNDr. Pavel Krejčí, Ph.D.

2025

• Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models

  RYNEŠ Jan IŠTVÁNKOVÁ Eva KRAFČÍKOVÁ Michaela LUCHINAT Enrico BARBIERI Letizia BANCI Lucia KAMARÝTOVÁ Kristýna LOJA Tomáš FAFÍLEK Bohumil RICO LLANOS Gustavo KREJČÍ Pavel MACUREK Libor TRANTÍRKOVÁ Silvie TRANTÍREK Lukáš

  Article in Periodical

  Communications Biology, year: 2025, volume: 8, edition: 1, DOI

• Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer

  ZLÍNSKÁ Vladimíra FEKETOVÁ Zuzana CZYREK Aleksandra Anna CHUDZIAN Julia ZIVKOVIC Martina Lenarcic URSACHI Vlad-Constantin DUDEJA Pooja FAFÍLEK Bohumil RYNEŠ Jan RICO LLANOS Gustavo KOUDELKA Adolf ROY Tanaya BIADUN Martyna RAŠKOVÁ Vendula SVOZILOVÁ Kateřina STROBLOVÁ Michaela KRZYSCIK Mateusz HRISTOVA Kalina KROWARSCH Daniel TRANTÍRKOVÁ Silvie ZAKRZEWSKA Malgorzata TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  MOLECULAR THERAPY-NUCLEIC ACIDS, year: 2025, volume: 36, edition: 1, DOI

2024

• Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy

  RICO LLANOS Gustavo SPOUTIL Frantisek BLAHOVÁ Eva KOUDELKA Adolf PROCHAZKOVA Michaela CZYREK Aleksandra Anna FAFÍLEK Bohumil PROCHAZKA Jan GONZÁLEZ LÓPEZ Marcos KŘIVÁNEK Jan SEDLACEK Radislav KRAKOW Deborah NONAKA Yosuke NAKAMURA Yoshikazu KREJČÍ Pavel

  Article in Periodical

  Journal of bone and mineral research, year: 2024, volume: 39, edition: 12, DOI

• Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2

  NĚMEC Václav REMEŠ Marek BEŇOVSKÝ Petr BÖCK Michael Christopher ŠRANKOVÁ Eliška WONG Jong Fu JULIEN Cros WILLIAMS Eleanor TSE Lap Hang SMIL David ENSAN Deeba ISAAC Methvin B AL-AWAR Rima GOMOLKOVÁ Regína URSACHI Vlad-Constantin FAFÍLEK Bohumil KAHOUNOVA Zuzana VICHOVA Rachel VACEK Ondrej BERGER Benedict-Tilman WELLS Carrow I CORONA Cesear R VASTA James D ROBERS Matthew B KREJČÍ Pavel SOUČEK Karel BULLOCK Alex N KNAPP Stefan PARUCH Kamil

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2024, volume: 67, edition: 15, DOI

• eIF4F controls ERK MAPK signaling in melanomas with BRAF and NRAS mutations

  VALČÍKOVÁ Barbora VADOVIČOVÁ Natália SMOLKOVÁ Karolína ZACPALOVÁ Magdaléna KREJČÍ Pavel LEE Shannon RAUCH Jens KOLCH Walter ALEXANDER von Kriegsheim DOROTÍKOVÁ Anna ANDRYSÍK Zdeněk VICHOVA Rachel VACEK Ondřej SOUČEK Karel ULDRIJAN Stjepan

  Article in Periodical

  Proceedings of the National Academy of Sciences of the United States of America, year: 2024, volume: 121, edition: 44, DOI

• Ligand bias underlies differential signaling of multiple FGFs via FGFR1

  KARL Kelly NUALA Del Piccolo LIGHT Taylor ROY Tanaya DUDEJA Pooja URSACHI Vlad-Constantin FAFÍLEK Bohumil KREJČÍ Pavel HRISTOVA Kalina

  Article in Periodical

  elife, year: 2024, volume: 12, edition: April 2024, DOI

• Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands

  KRZYSCIK Mateusz A KARL Kelly DUDEJA Pooja KREJČÍ Pavel HRISTOVA Kalina

  Article in Periodical

  CYTOKINE & GROWTH FACTOR REVIEWS, year: 2024, volume: 78, edition: August 2024, DOI

2023

• Lékařská biologie II. Genetika a molekulární medicína

  SLABÝ Ondřej SLANINOVÁ Iva ŠMAJS David ŠÁNA Jiří ROTREKL Vladimír KREJČÍ Pavel ULDRIJAN Stjepan BOSÁK Juraj SLABÁ Kateřina ŠEVČÍKOVÁ Sabina

  Monograph

  Year: 2023, edition: Vyd. 1., number of pages: 227 s.

• Nanodiamonds as artificial proteins for regulation of a cell signalling system

  CÍGLER Petr BÁLEK Lukáš HAVLÍK Jan KREJČÍ Pavel TRANTÍREK Lukáš TRANTÍRKOVÁ Silvie

  Patent

  Publisher: European Patent Office, state: Germany, patent's number: EP3645018B1, year: 2023

• Nanodiamonds as artificial proteins for regulation of a cell signalling system

  CÍGLER Petr BÁLEK Lukáš HAVLÍK Jan KREJČÍ Pavel TRANTÍREK Lukáš TRANTÍRKOVÁ Silvie

  Patent

  Publisher: United States Patent and Trademark Office, state: United States of America, patent's number: US11744855B2, year: 2023