RNDr. Pavel Krejčí, Ph.D.

2018

• Registr Achondroplázie REACH

  PEŠL Martin SKUTKOVÁ Linda STRENKOVÁ Jana KREJČÍ Pavel

  Year: 2018, type:

• Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies

  BOSÁKOVÁ Michaela VAŘECHA Miroslav HAMPL Marek DURAN Ivan NITĂ Alexandru BUCHTOVÁ Marcela DOSEDELOVA Hana MACHÁT Radek XIE Yangli NI Zhenhong MARTIN Jorge H. CHEN Lin JANSEN Gert KRAKOW Deborah KREJČÍ Pavel

  Article in Periodical

  Human molecular genetics, year: 2018, volume: 27, edition: 6, DOI

• The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

  FAFÍLEK Bohumil BÁLEK Lukáš BOSÁKOVÁ Michaela VAŘECHA Miroslav NITĂ Alexandru GREGOR Tomáš GUDERNOVÁ Iva KŘENOVÁ Jitka GHOSH S. PISKÁČEK Martin JONATOVA Lucie ČERNOHORSKÁ Nicole ZIEBA J.T. KOSTAS M. HAUGSTEN E.M. WESCHE J. ERNEUX C. TRANTÍREK Lukáš KRAKOW D. KREJČÍ Pavel

  Article in Periodical

  SCIENCE SIGNALING, year: 2018, volume: 11, edition: 548, DOI

• The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling

  CSUKASI F. DURAN I. BARAD M. BÁRTA Tomáš GUDERNOVÁ Iva TRANTÍREK Lukáš MARTIN J.H. KUO C.Y. WOODS J. LEE H. COHN D.H. KREJČÍ Pavel KRAKOW D.

  Article in Periodical

  Science Translational Medicine, year: 2018, volume: 10, edition: 459, DOI

2017

• A Chaperone Complex Formed by HSP47, FKBP65 and BiP Modulates Telopeptide Lysyl Hydroxylation of Type I Procollagen

  DURAN Ivan MARTIN Jorge H. WEIS Mary Ann KREJČÍ Pavel KONIK Peter LI Bing ALANAY Yasemin LIETMAN Caressa LEE Brendan EYRE David COHN Daniel H. KRAKOW Deborah

  Article in Periodical

  Journal of Bone and Mineral Research, year: 2017, volume: 32, edition: 6, DOI

• A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation

  BERNATÍK Ondřej RADASZKIEWICZ Tomasz Witold BĚHAL Martin DAVE Zankruti WITTE Florian MAHL Annika ČERNOHORSKÁ Nicole KREJČÍ Pavel STRICKER Sigmar BRYJA Vítězslav

  Article in Periodical

  Frontiers in Cell and Developmental Biology, year: 2017, volume: 5, edition: MAY, DOI

• ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

  BÁLEK Lukáš GUDERNOVÁ Iva VESELA Iva HAMPL Marek ORALOVÁ Veronika BOSÁKOVÁ Michaela VAŘECHA Miroslav NĚMEC Pavel HALL Terence ABBADESSA Giovanni HATCH Nan BUCHTOVÁ marcela KREJČÍ Pavel

  Article in Periodical

  Bone, year: 2017, volume: 105, edition: DEC 2017, DOI

• Differences in anterior-posterior sensitivity of early limb bud cell to FGF/WNT treatment

  KILLINGER Michael HRUBÁ Eva VAŘECHA Miroslav KREJČÍ Pavel BUCHTOVÁ marcela

  Conference abstract

  Year: 2017, type: Conference abstract

• Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

  GUDERNOVÁ Iva BÁLEK Lukáš VAŘECHA Miroslav FIALOVÁ KUČEROVÁ Jana BOSÁKOVÁ Michaela FAFÍLEK Bohumil PALUŠOVÁ Veronika ULDRIJAN Stjepan TRANTÍREK Lukáš KREJČÍ Pavel

  Article in Periodical

  Oncotarget, year: 2017, volume: 8, edition: 65, DOI

• One reporter for in-cell activity profiling of majority of protein kinase oncogenes

  GUDERNOVÁ Iva TRANTÍRKOVÁ Silvie EL GHANNAMOVÁ Barbora FAFÍLEK Bohumil VAŘECHA Miroslav BÁLEK Lukáš HRUBÁ Eva JONÁTOVÁ Lucie JELÍNKOVÁ Iva BOSÁKOVÁ Michaela TRANTÍREK Lukáš MAYER Jiří KREJČÍ Pavel

  Article in Periodical

  eLife, year: 2017, volume: 6, edition: "e21536", DOI