prof. MUDr. Mgr. Marek Mráz, Ph.D.

2019

• High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade During Ibrutinib Therapy in Patients with CLL.

  CHIODIN G. DUTTON D. MARTINO EA. DRENNAN S. TRACY I. ONDRIŠOVÁ Laura HENDERSON I. D´AVOLA A. PITSILLIDOU Ch. MRÁZ Marek JOHNSON P. DUNCOMBE A. PACKHAM G. STEELE A. PARKER H. BONFIGLIO S. SCARFO L. SUTTON LA. GHIA P. ROSE-ZERILLI MJJ. STREFFORD J. STEVENSON F. FORCONI F.

  Conference abstract

  Year: 2019, type: Conference abstract

• High surface tumor IgM levels associate with reduced response duration and with BTK bypass during ibrutinib therapy in CLL patients

  CHIODIN G. DUTTON D. MARTINO E. ONDRIŠOVÁ Laura PITSILLIDOU Ch. HENDERSON I. TRACY I. DRENNAN S. D´AVOLA A. MRÁZ Marek JOHNSON P. DUNCOMBE A. PACKHAM G. STEELE A. SCARFO L. GHIA P. ROSE-ZERILLI M. STREFFORD J. STEVENSON F. FORCONI F.

  Conference abstract

  Year: 2019, type: Conference abstract

• Impact of gene mutations and chromosomal aberrations on progression-free survival in chronic lymphocytic leukemia patients treated with front-line chemoimmunotherapy: Clinical practice experience

  ŠPUNAROVÁ Michaela TOM Nikola PAVLOVÁ Šárka MRÁZ Marek BRYCHTOVÁ Yvona DOUBEK Michael PANOVSKÁ Anna SKUHROVÁ FRANCOVÁ Hana BRZOBOHATÁ Anna POSPÍŠILOVÁ Šárka MAYER Jiří TRBUŠEK Martin

  Article in Periodical

  Leukemia Research, year: 2019, volume: 81, edition: JUN 2019, DOI

• Jak vlastně fungují anti CD 20 monoklonální protilátky? Víme více po 20 letech jejich používání?

  MRÁZ Marek

  Conference abstract

  Year: 2019, type: Conference abstract

• Komplexní mechanismy účinku inhibitorů „BCR signalizace“ a vzniku rezistence na tuto cílenou léčbu u chronické lymfocytární leukemie

  KOŠŤÁLOVÁ Lenka ŠEDA Václav MRÁZ Marek

  Article in Periodical

  Transfúze a hematologie dnes, year: 2019, volume: 25, edition: 4

• Mechanism of leukemia cell adaptation to targeted therapy in chronic lymphocytic leukemia

  ONDRIŠOVÁ Laura ŠEDA Václav AMRUZ ČERNÁ Kateřina MLADONICKÁ PAVLASOVÁ Gabriela VOJÁČKOVÁ Eva OPPELT Jan FILIP Daniel ŠANDOVÁ Veronika MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2019, type: Conference abstract

• MicroRNA a regulace BCR signalizace u B buněčných malignit: Biomarkery a terapeutické implikace.

  MRÁZ Marek

  Conference abstract

  Year: 2019, type: Conference abstract

• MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells

  AMRUZ ČERNÁ Kateřina OPPELT Jan CHOCHOLA Václav MUSILOVÁ Kateřina ŠEDA Václav PAVLASOVÁ Gabriela RADOVÁ Lenka ARIGONI M. CALOGERO R.A. BENES V. TRBUŠEK Martin BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka MRÁZ Marek

  Article in Periodical

  Leukemia, year: 2019, volume: 33, edition: 2, DOI

• Nové mechanismy regulace B buněčné signalizace u leukémií a lymfomů.

  MRÁZ Marek

  Conference abstract

  Year: 2019, type: Conference abstract

• Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells

  BOUDNÝ Miroslav ZEMANOVÁ Jana KHIRSARIYA PrashantKumar BORSKÝ Marek VERNER Jan ČERNÁ Jana OLTOVÁ Alexandra ŠEDA Václav MRÁZ Marek JAROŠ Josef JAŠKOVÁ Zuzana ŠPUNAROVÁ Michaela BRYCHTOVÁ Yvona SOUČEK Karel DRÁPELA Stanislav KAŠPÁRKOVÁ Marie MAYER Jiří PARUCH Kamil TRBUŠEK Martin

  Article in Periodical

  Haematologica, year: 2019, volume: 104, edition: 12, DOI