Mgr. Bohumil Fafílek, Ph.D.

2017

• One reporter for in-cell activity profiling of majority of protein kinase oncogenes

  GUDERNOVÁ Iva TRANTÍRKOVÁ Silvie EL GHANNAMOVÁ Barbora FAFÍLEK Bohumil VAŘECHA Miroslav BÁLEK Lukáš HRUBÁ Eva JONÁTOVÁ Lucie JELÍNKOVÁ Iva BOSÁKOVÁ Michaela TRANTÍREK Lukáš MAYER Jiří KREJČÍ Pavel

  Article in Periodical

  eLife, year: 2017, volume: 6, edition: "e21536", DOI

• Statins do not inhibit the FGFR signaling in chondrocytes

  FAFÍLEK Bohumil HAMPL Marek ŘIČÁNKOVÁ Nikola VESELA I. BÁLEK Lukáš BOSÁKOVÁ Michaela GUDERNOVÁ Iva VAŘECHA Miroslav BUCHTOVÁ marcela KREJČÍ Pavel

  Article in Periodical

  Osteoarthritis and Cartilage, year: 2017, volume: 25, edition: 9, DOI

2016

• Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity

  JANECKOVA L FAFÍLEK Bohumil KRAUSOVA M HORAZNA M VOJTECHOVA M ALBERICH-JORDA M SLONCOVA E GALUSKOVA K SEDLACEK R ANDEROVA M KORINEK V

  Article in Periodical

  GENESIS, year: 2016, volume: 54, edition: 3, DOI

2015

• HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-kappa B Signaling and Promotes Tissue Damage-Associated Tumorigenesis

  JANECKOVA L POSPÍCHALOVÁ Vendula FAFÍLEK Bohumil VOJTECHOVA M TURECKOVA J DOBES J DUBUISSEZ M LEPRINCE D BALOGHOVA N HORAZNA M HLAVATA A STANCIKOVA J SLONCOVA E GALUSKOVA K STRNAD H KORINEK V

  Article in Periodical

  MOLECULAR CANCER RESEARCH, year: 2015, volume: 13, edition: 7, DOI

• NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling

  STANCIKOVA J KRAUSOVA M KOLAR M FAFÍLEK Bohumil SVEC J SEDLACEK R NEROLDOVA M DOBES J HORAZNA M JANECKOVA L VOJTECHOVA M OLIVERIUS M JIRSA Milan KORINEK V

  Article in Periodical

  Cellular Signalling, year: 2015, volume: 27, edition: 2, DOI

2013

• Expression of the chicken GDNF family receptor alpha-1 as a marker of spermatogonial stem cells

  MUCKSOVA J KALINA J BAKST M YAN H BRILLARD JP BENESOVA B FAFÍLEK Bohumil HEJNAR J TREFIL P

  Article in Periodical

  ANIMAL REPRODUCTION SCIENCE, year: 2013, volume: 142, edition: 1-2, DOI

• Troy, a Tumor Necrosis Factor Receptor Family Member, Interacts With Lgr5 to Inhibit Wnt Signaling in Intestinal Stem Cells

  FAFÍLEK Bohumil KRAUSOVA M VOJTECHOVA M POSPÍCHALOVÁ Vendula TUMOVA L SLONCOVA E HURANOVA M STANCIKOVA J HLAVATA A SVEC J SEDLACEK R LUKSAN O OLIVERIUS M VOSKA Ivan JIRSA Milan PACES J KOLAR M KRIVJANSKA M KLIMESOVA K TLASKALOVA-HOGENOVA H KORINEK V

  Article in Periodical

  Gastroenterology, year: 2013, volume: 144, edition: 2, DOI

2011

• Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling

  DOUBRAVSKA L KRAUSOVA M GRADL D VOJTECHOVA M TUMOVA L LUKAS J VALENTA T POSPÍCHALOVÁ Vendula FAFÍLEK Bohumil PLACHY J SEBESTA O KORINEK V

  Article in Periodical

  Cellular Signalling, year: 2011, volume: 23, edition: 5, DOI

• Generation of Two Modified Mouse Alleles of the Hic1 Tumor Suppressor Gene

  POSPÍCHALOVÁ Vendula TURECKOVA J FAFÍLEK Bohumil VOJTECHOVA M KRAUSOVA M LUKAS J SLONCOVA E TAKÁČOVÁ Sylvia DIVOKÝ Vladimír LEPRINCE D PLACHY J KORINEK V

  Article in Periodical

  GENESIS, year: 2011, volume: 49, edition: 3, DOI

2009

• Dazap2 modulates transcription driven by the Wnt effector TCF-4

  LUKAS J MAZNA P VALENTA T DOUBRAVSKA L POSPÍCHALOVÁ Vendula VOJTECHOVA M FAFÍLEK Bohumil IVANEK R PLACHY J NOVAK J KORINEK V

  Article in Periodical

  Nucleic Acids Research, year: 2009, volume: 37, edition: 9, DOI