Mgr. Václav Šeda, Ph.D.

2021

• GAB1 – novel regulator of migration capacity and tonic AKT activity in CLL: Implications for combinatorial therapy with BCR inhibitors.

  ŠEDA Václav HOFERKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA Daniel VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna DOUBEK Michael MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• GAB1 Regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia: novel therapeutic target

  MRÁZ Marek ŠEDA Václav HOFERKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA Daniel VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna DOUBEK Michael MAYER Jiří

  Conference abstract

  Year: 2021, type: Conference abstract

• GAB1 reguluje tonickou AKT signalizaci a migraci buněk chronické lymfatické leukémie: implikace pro kombinační léčbu s BCR inhibitory.

  ŠEDA Václav VOJÁČKOVÁ Eva ONDRIŠOVÁ Laura KOŠŤÁLOVÁ Lenka SHARMA Sonali LOJA Tomáš ZICHA D. VERNER Jan POSPÍŠILOVÁ Šárka BRYCHTOVÁ Yvona PANOVSKÁ Anna TAN Zhuowen ZHANG Shelley DOUBEK Michael MAYER Jiří MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• Ibrutinib Blocks CD40 Signalling in CLL in Vivo by Reducing TRAF4 Levels.

  SHARMA Sonali MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav AMRUZ ČERNÁ Kateřina HOFERKOVÁ Eva FILIP Daniel ONDRIŠOVÁ Laura ŠANDOVÁ Veronika KOŠŤÁLOVÁ Lenka FARIA ZENI Pedro BORSKÝ Marek OPPELT Jan LISKOVA K. KŘEN Leoš JANÍKOVÁ Andrea POSPÍŠILOVÁ Šárka FERNANDES S. SHEHATA M. RASSENTI L. JAEGER U. DOUBEK Michael DAVIDS M. BROWN J. MAYER Jiří KIPPS T. MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K delta inhibitor idelalisib

  ŠANDOVÁ Veronika MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav AMRUZ ČERNÁ Kateřina SHARMA Sonali PALUŠOVÁ Veronika BRYCHTOVÁ Yvona POSPÍŠILOVÁ Šárka FERNANDES S.M. PANOVSKÁ Anna DOUBEK Michael DAVIDS M.S. BROWN J.R. MAYER Jiří MRÁZ Marek

  Article in Periodical

  haematologica, year: 2021, volume: 106, edition: 11, DOI

• IL4-STAT6 Signaling Induces CD20 in Chronic Lymphocytic Leukemia and This Axis Is Repressed by PI3Kδ Inhibitor Idelalisib.

  ŠANDOVÁ Veronika MRÁZ Marek MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav PALUŠOVÁ Veronika BRYCHTOVÁ Yvona FERNANDES S. DOUBEK Michael DAVIDS M. BROWN J.

  Conference abstract

  Year: 2021, type: Conference abstract

• miR-29 influences CD40 signaling in chronic lymphocytic leukemia (CLL): and axis affected by BCR inhibitors.

  SHARMA Sonali MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav AMRUZ ČERNÁ Kateřina VOJÁČKOVÁ E. FILIP Daniel ONDRIŠOVÁ Laura ŠANDOVÁ Veronika KOŠŤÁLOVÁ Lenka FARIA ZENI Pedro MEDKOVÁ Michaela ZELINKOVÁ M. VEČEŘA Josef BOUDNÝ Miroslav OPPELT Jan LISKOVA K. KŘEN Leoš JANÍKOVÁ Andrea POSPÍŠILOVÁ Šárka FERNANDES SM. SHEHATA M RASSENTI LZ. JAEGER U. DOUBEK Michael DAVIDS MS. BROWN JR. MAYER Jiří KIPPS TJ. MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• miR-29 Modulates CD40 Signaling in Chronic Lymphocytic Leukemia by Targeting TRAF4: an Axis Affected by BCR inhibitors

  SHARMA Sonali MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav AMRUZ ČERNÁ Kateřina VOJÁČKOVÁ Eva FILIP Daniel ONDRIŠOVÁ Laura ŠANDOVÁ Veronika KOŠŤÁLOVÁ Lenka FARIA ZENI Pedro BORSKÝ Marek OPPELT Jan LIŠKOVÁ Květoslava KŘEN Leoš JANÍKOVÁ Andrea POSPÍŠILOVÁ Šárka FERNANDES Stacey M. SHEHATA Medhat RASSENTI Laura Z. JAEGER Ulrich DOUBEK Michael DAVIDS Matthew S. BROWN Jennifer R. MAYER Jiří KIPPS Thomas J. MRÁZ Marek

  Article in Periodical

  Blood, year: 2021, volume: 137, edition: 18, DOI

• miR-29 Modulates CD40 Signaling in Chronic Lymphocytic Leukemia by Targeting TRAF4: an Axis Affected by BCR.

  SHARMA Sonali MLADONICKÁ PAVLASOVÁ Gabriela ŠEDA Václav VOJÁČKOVÁ E. ONDRIŠOVÁ Laura ŠANDOVÁ Veronika FARIA ZENI Pedro FILIP Daniel KOŠŤÁLOVÁ Lenka MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract

• miR-29-TRAF4 axis is a novel regulator of CD40 signaling in malignant B cells.

  SHARMA Sonali ŠEDA Václav VOJÁČKOVÁ E. MLADONICKÁ PAVLASOVÁ Gabriela FILIP Daniel ONDRIŠOVÁ Laura ŠANDOVÁ Veronika KOŠŤÁLOVÁ Lenka FARIA ZENI Pedro BORSKÝ Marek POSPÍŠILOVÁ Šárka SHEHATA M. RASSENTI L. JAEGER U. DOUBEK M DAVIDS M. BROWN J. MAYER Jiří KIPPS T. MRÁZ Marek

  Conference abstract

  Year: 2021, type: Conference abstract