Mgr. Robert Helma, Ph.D.

2022

• Distinct p53 phospohrylation patterns in chronic lymphocytic leukemia patients are reflected in circumjacent pathways activation upon DNA damage.

  PEŠOVÁ Michaela MANČÍKOVÁ Veronika HELMA Robert PAVLOVÁ Šárka HEJRET Václav TAUŠ Petr HYNŠT Jakub PLEVOVÁ Karla KOTAŠKOVÁ Jana MALČÍKOVÁ Jitka POSPÍŠILOVÁ Šárka

  Conference abstract

  Year: 2022, type: Conference abstract

2021

• Fosforylace proteinu p53: vliv na aktivitu dráhy p53 po poškození DNA u chronické lymfocytární leukémie.

  PEŠOVÁ Michaela MANČÍKOVÁ Veronika PAVLOVÁ Šárka HELMA Robert MALČÍKOVÁ Jitka ŽENATOVÁ Marcela HEJRET Václav TAUŠ Petr KOTAŠKOVÁ Jana PLEVOVÁ Karla DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka

  Conference abstract

  Year: 2021, type: Conference abstract

• Phosphorylation patterns of tumor suppressor P53 and their impact on the P53 pathway activity in chronic lymphocytic leukemia.

  PEŠOVÁ Michaela MANČÍKOVÁ Veronika PAVLOVÁ Šárka HELMA Robert MALČÍKOVÁ Jitka ŽENATOVÁ Marcela HEJRET Václav TAUŠ Petr KOTAŠKOVÁ Jana PLEVOVÁ Karla DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka

  Conference abstract

  Year: 2021, type: Conference abstract

2019

• p53 Binds Preferentially to Non-B DNA Structures Formed by the Pyrimidine-Rich Strands of GAA center dot TTC Trinucleotide Repeats Associated with Friedreich's Ataxia

  HELMA R. BAZANTOVA P. PETR M. ADAMIK M. RENCIUK D. TICHY V. PASTUCHOVA A. SOLDANOVA Z. PECINKA P. BOWATER R.P. FOJTA Miroslav BRAZDOVA M.

  Article in Periodical

  Molecules, year: 2019, volume: 24, edition: 11, DOI

2016

• Electrochemical sensing of concanavalin A and ovalbumin interaction in solution

  VARGOVA V HELMA R PALECEK E OSTATNA V

  Article in Periodical

  Analytica Chimica Acta, year: 2016, volume: 935, DOI

• p53 interactions with DNA quadruplexes

  ADÁMIK Matej KREJČÍ Aneta RENČIUK Daniel PETR Marek BAŽANTOVÁ Pavla HELMA Robert POLÁŠKOVÁ Alena BÁBKOVÁ Zuzana KEJNOVSKÁ Iva NAVRÁTILOVÁ Lucie VORLÍČKOVÁ Michaela BRÁZDOVÁ Marie

  Appeared in Conference without Proceedings

  Year: 2016, type: Appeared in Conference without Proceedings

• p53 Specifically Binds Triplex DNA In Vitro and in Cells

  BRÁZDOVÁ Marie TICHÝ Vlastimil HELMA Robert BAŽANTOVÁ Pavla POLÁŠKOVÁ Alena KREJČÍ Aneta PETR Marek NAVRÁTILOVÁ Lucie TICHÁ Olga NEJEDLÝ Karel BENNINK Martin L SUBRAMANIAM Vinod BÁBKOVÁ Zuzana MARTÍNEK Tomáš LEXA Matej ADÁMIK Matej

  Article in Periodical

  PLOS ONE, year: 2016, volume: 11, edition: 12, DOI

• Wild-type p53 binds to MYC promoter G-quadruplex

  PETR Marek HELMA Robert POLÁŠKOVÁ Alena KREJČÍ Aneta DVOŘÁKOVÁ Zuzana KEJNOVSKÁ Iva NAVRÁTILOVÁ Lucie ADÁMIK Matej VORLÍČKOVÁ Michaela BRÁZDOVÁ Marie RUMÍŠKOVÁ Gabriela

  Article in Periodical

  Bioscience Reports, year: 2016, volume: 36, DOI