Mgr. Veronika Navrkalová, Ph.D.

2017

• Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients

  KANTOROVÁ Barbara MALČÍKOVÁ Jitka STRÁNSKÁ Kamila BORSKY Marek PLEVOVÁ Karla SMARDOVA Jana RADOVÁ Lenka TOM Nikola TRBUSEK Martin DIVISKOVA Eva FRANCOVA SKUHROVA Hana NAVRKALOVÁ Veronika DOUBEK Michael BRYCHTOVA Yvona MAYER Jiří POSPÍŠILOVÁ Šárka

  Article in Periodical

  British journal of haematology, year: 2017, volume: 178, edition: 6, DOI

• The level of cyclin-dependent kinase inhibitor p27 Kip1 after DNA damage is retained in chronic lymphocytic leukemia cells

  RAŠKOVÁ KAFKOVÁ L. NAVRKALOVÁ Veronika JAROŠOVÁ Marie LOJA Tomáš ČERNÁ Jana FIALOVÁ KUČEROVÁ Jana KRIEGOVÁ E. PROCHÁZKA V. NOVÁK Zdeněk ŠIMKOVÁ Dagmar POSPÍŠILOVÁ Šárka DIVOKÝ Vladimír

  Conference abstract

  Year: 2017, type: Conference abstract

2016

• Ability to downregulate the level of cyclin-dependent kinase inhibitor P27KIP1 after DNA damage is retained in chronic lymphocytic leukemia cells with fuctional ATM/p53 signaling pathway.

  RAŠKOVÁ KAFKOVÁ L. JAROŠOVÁ M. NAVRKALOVÁ Veronika LOJA Tomáš CHOVANCOVÁ Jana FIALOVÁ KUČEROVÁ J. ŠIMKOVÁ D. PROCHÁZKA V. POSPÍŠILOVÁ Šárka DIVOKÝ Vladimír

  Conference abstract

  Year: 2016, type: Conference abstract

• ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: Enrichment in subset 2 is associated with markedly short telomeres

  NAVRKALOVÁ Veronika YOUNG Emma BALIAKAS Panagiotis RADOVÁ Lenka SUTTON Lesley-Ann PLEVOVÁ Karla MANSOURI Larry LJUNGSTRÖM Viktor NTOUFA Stavroula DAVIS Zadie JULIUSSON Gunnar SMEDBY Karin E. BELESSI Chrysoula PANAGIOTIDIS Panagiotis TOULOUMENIDOU Tasoula DAVI Frederic LANGERAK Anton W. GHIA Paolo STREFFORD Jonathan C. OSCIER David MAYER Jiří STAMATOPOULOS Kostas POSPÍŠILOVÁ Šárka ROSENQUIST Richard TRBUŠEK Martin

  Article in Periodical

  Haematologica, year: 2016, volume: 101, edition: 9, DOI

• Mutations in SF3B1 gene are selected independently on ATM/TP53 status and reduce the time to first treatment in CLL patients.

  HLOŽKOVÁ Michaela FIGULOVÁ Jana NAVRKALOVÁ Veronika MALČÍKOVÁ Jitka ŠMARDOVÁ Jana TOM Nikola BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka TRBUŠEK Martin

  Conference abstract

  Year: 2016, type: Conference abstract

2015

• Akumulace mutací v genu SF3B1 u pacientů s chronickou lymfocytární leukémií vykazujících dysfunkci p53 dráhy

  HLOŽKOVÁ Michaela NAVRKALOVÁ Veronika MALČÍKOVÁ Jitka DIVÍŠKOVÁ Eva BRYCHTOVÁ Yvona DOUBEK Michael MAYER Jiří TRBUŠEK

  Conference abstract

  Year: 2015, type: Conference abstract

• Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification

  TE RAA G.D. MOERLAND P.D. LEEKSMA A.C. DERKS I.A. YIGITTOP H. LADDACH N. LODEN-VAN STRAATEN M. NAVRKALOVÁ Veronika TRBUŠEK Martin LUIJKS D.M. ZENZ T. SKOWRONSKA A. HOOGENDOORN M. STANKOVIC T. VAN OERS M.H. ELDERING E. KATER A.P.

  Article in Periodical

  CELL DEATH & DISEASE, year: 2015, volume: 6, edition: august, DOI

• ATM mutations are stable during the course of chronic lymphocytic leukemia.

  FIGULOVÁ Jana NAVRKALOVÁ Veronika BRYCHTOVÁ Yvona MAYER Jiří TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• ATM mutations in major stereotyped CLL subsets: enrichment in subset #2 is associated with unfavourable outcome

  NAVRKALOVÁ Veronika YOUNG E. BALIAKAS P. RADOVÁ Lenka PLEVOVÁ Karla SUTTON LA. MANSOURI L. LJUNGSTROM V. NTOUFA S. DAVIS Z. JULIUSSON G. SMEDBY K. BELESSI Ch. PANAGIOTIDIS P. DAVI F. LANGERAK A. GHIA P. STREFFORD J. OSICER D. STAMATOPOULOS K. POSPÍŠILOVÁ Šárka ROSENQUIST R. TRBUŠEK Martin

  Conference abstract

  Year: 2015, type: Conference abstract

• EGR2 mutations in chronic lymphocytic leukemia - a new bad player?

  YOUNG E. NORENBERG D. LJUNGSTROM V. MANSOURI L. PLEVOVÁ Karla BALIAKAS P. ROSSI D. NAVRKALOVÁ Veronika SUTTON LA. SMEDBY EK. JULIUSSON G. BELESSI Ch. PANAGIOTIDIS P. CHIORAZZI N. DAVI F. LANGERAK A. GAIDANO G. GHIA P. STAMATOPOULOS K. POSPÍŠILOVÁ Šárka ZENZ T. ROSENQUIST R. DAMM F.

  Conference abstract

  Year: 2015, type: Conference abstract