prof. MUDr. Michael Doubek, Ph.D.

2024

• A novel thrombocytopenia-4-causing CYCS gene variant decreases caspase activity: Three-generation study

  ŠTIKA Jiří PEŠOVÁ Michaela STAŇO KOZUBÍK Kateřina SKALNÍKOVÁ Magdalena DOSTÁLOVÁ Lenka LOJA Tomas RADOVÁ Lenka PALUŠOVÁ Veronika RÉBLOVÁ Kamila VRZALOVÁ Zuzana BLAHÁKOVÁ Ivona TRIZULJAK Jakub ULDRIJAN Stjepan BLATNÝ Jan ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

  Article in Periodical

  British journal of haematology, year: 2024, DOI

• FoxO1/Rictor axis induces a non-genetic adaptation to Ibrutinib via Akt activation in chronic lymphocytic leukemia

  ONDRIŠOVÁ Laura ŠEDA Václav HLAVÁČ Kryštof PAVELKOVÁ Petra HOFERKOVÁ Eva CHIODIN Giorgia KOŠŤÁLOVÁ Lenka MLADONICKÁ PAVLASOVÁ Gabriela FILIP Daniel VEČEŘA Josef FARIA ZENI Pedro OPPELT Jan KAHOUNOVÁ Zuzana VICHOVA Rachel SOUČEK Karel PANOVSKÁ Anna PLEVOVÁ Karla POSPÍŠILOVÁ Šárka ŠIMKOVIČ Martin VRBACKÝ Filip LYSÁK Daniel FERNANDES Stacey M. DAVIDS M.S. MAIQUES-DIAZ Alba CHARALAMPOPOULOU Stella MARTIN-SUBERO Jose I. BROWN Jenifer R. DOUBEK Michael MAYER Jiří MRÁZ Marek

  Article in Periodical

  The Journal of Clinical Investigation, year: 2024, DOI

• Gamma-delta T cells in newly diagnosed patients with chronic lymphocytic leukaemia

  KNIGHT Andrea PISKÁČEK Martin TOMANDLOVÁ Marie ŠKABRAHOVÁ Hana ORSULOVA Martina DOUBEK Michael

  Year: 2024, type:

• Impact of thrombocytopenia-associated c.-118C>T and c.-140C>G ANKRD26 5’UTR variants in three-generational pedigree

  TRIZULJAK Jakub LIKAVCOVÁ Paulína STAŇO KOZUBÍK Kateřina VRZALOVÁ Zuzana HYNŠT Jakub DEISSOVÁ Tereza ŠTIKA Jiří RADOVÁ Lenka PRUDKOVÁ Marie VACULOVA Jana BLAHÁKOVÁ Ivona SMEJKAL Petr KAMELANDER Jan POSPÍŠILOVÁ Šárka DOUBEK Michael

  Article in Periodical

  Platelets, year: 2024, volume: 35, edition: 1, DOI

• Innate effector gamma-delta T cells in newly diagnosed patients with chronic lymphocytic leukaemia

  KNIGHT Andrea PISKÁČEK Martin TOMANDLOVÁ Marie ŠKABRAHOVÁ Hana ORSULOVA Martina DOUBEK Michael

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

• Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients

  NAVRKALOVÁ Veronika PLEVOVÁ Karla RADOVÁ Lenka PORC Jakub Paweł PÁL Karol MALČÍKOVÁ Jitka PAVLOVÁ Šárka DOUBEK Michael PANOVSKÁ Anna KOTAŠKOVÁ Jana POSPÍŠILOVÁ Šárka

  Article in Periodical

  British journal of haematology, year: 2024, volume: 204, edition: 1, DOI

• Real-world data on diagnostics, treatment and outcomes of patients with hairy cell leukemia: The HCL-CLLEAR study

  PANOVSKÁ Anna ZAK Pavel JURKOVA Tereza ARPÁŠ Tomáš BRYCHTOVÁ Yvona VAŠÍKOVÁ Alžběta HRABČÁKOVÁ Viera PRCHLÍKOVÁ Adéla FILIPOVÁ Martina DOUBEK Michael

  Article in Periodical

  Hematological Oncology, year: 2024, volume: 42, edition: 3, DOI

• Serum chemistry profiling and prognostication in systemic mastocytosis: a registry-based study of the ECNM and GREM

  LUEBKE Johannes SCHMID Alicia CHRISTEN Deborah ELBERINK Hanneke N G Oude SPAN Lambert F R NIEDOSZYTKO Marek GORSKA Aleksandra LANGE Magdalena GLEIXNER Karoline V HADZIJUSUFOVIC Emir STEFAN Alex ANGELOVA-FISCHER Irena ZANOTTI Roberta BONIFACIO Massimiliano BONADONNA Patrizia SHOUMARIYEH Khalid NIKOLAS von Bubnoff MUELLER Sabine PERKINS Cecelia ELENA Chiara MALCOVATI Luca HAGGLUND Hans MATTSSON Mattias PARENTE Roberta VARKONYI Judit FORTINA Anna Belloni CAROPPO Francesca BROCKOW Knut ZINK Alexander BREYNAERT Christine LEVEN Toon YAVUZ Akif Selim DOUBEK Michael SABATO Vito SCHUG Tanja HARTMANN Karin TRIGGIANI Massimo GOTLIB Jason HERMINE Olivier AROCK Michel KLUIN-NELEMANS Hanneke C PANSE Jens SPERR Wolfgang R VALENT Peter REITER Andreas SCHWAAB Juliana

  Article in Periodical

  Blood advances, year: 2024, volume: 8, edition: 11, DOI

• Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug

  HOFERKOVÁ Eva ŠEDA Václav CESNÁRIKOVÁ Soňa VERNER Jan LOJA Tomáš MATULOVÁ Květoslava SKUHROVÁ FRANCOVÁ Hana ONDROUŠKOVÁ Eva FILIP Daniel BLAVET Nicolas BOUDNÝ Miroslav MLADONICKÁ PAVLASOVÁ Gabriela VEČEŘA Josef ONDRIŠOVÁ Laura PAVELKOVÁ Petra HLAVÁČ Kryštof KOŠŤÁLOVÁ Lenka MICHAELOU Androniki POSPÍŠILOVÁ Šárka DORAZILOVÁ Jana CHOCHOLA Václav JAROŠ Josef DOUBEK Michael JAROŠOVÁ Marie HAMPL Aleš VOJTOVÁ Lucy KŘEN Leoš MAYER Jiří MRÁZ Marek

  Article in Periodical

  Leukemia, year: 2024, volume: 38, edition: 8, DOI

• Therapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL

  CHATZIKONSTANTINOU Thomas SCARFO Lydia MINGA Eva KARAKATSOULIS Georgios CHAMOU Dimitra KOTAŠKOVÁ Jana IACOBONI Gloria DEMOSTHENOUS Christos ALBI Elisa ALCOCEBA Miguel AL-SHEMARI Salem AURRAN-SCHLEINITZ Therese BACCHIARRI Francesca CHATZILEONTIADOU Sofia COLLADO Rosa DAVIS Zadie DANIEL de Deus Santos Marcos DIMOU Maria DMITRIEVA Elena DONALDSON David GIMENA Dos Santos DRETA Barbara EFSTATHOPOULOU Maria EL-ASHWAH Shaimaa ENRICO Alicia FRYGIER Andrzej GALIMBERTI Sara GALITZIA Andrea GIMENO Eva GUARENTE Valerio GUIEZE Romain HARROP Sean HATZIMICHAEL Eleftheria HERISHANU Yair HERNANDEZ-RIVAS Jose-angel JAKSIC Ozren KALICINSKA Elzbieta LARIBI Kamel KARAKUS Volkan KATER Arnon P KHO Bonnie KISLOVA Maria KONSTANTINOU Eliana KOREN-MICHOWITZ Maya KOTSIANIDIS Ioannis KUBOVA Zuzana LABRADOR Jorge LAD Deepesh LAURENTI Luca LONGVAL Thomas LOPEZ-GARCIA Alberto MARQUET Juan MASLEJOVA Stanislava MAYOR-BASTIDA Carlota MIHALJEVIC Biljana MILOSEVIC Ivana MIRAS Fatima MOIA Riccardo MORAWSKA Marta NATH Uttam K NAVARRO-BAILON Almudena OLIVIERI Jacopo PANOVSKA-STAVRIDIS Irina PAPAIOANNOU Maria PIERIE Cheyenne PUIGGROS Anna REDA Gianluigi RIGOLIN Gian M RUCHLEMER Rosa SCHIPANI Mattia SCHIWITZA Annett SHEN Yandong SHOKRALLA Tereza SIMKOVIC Martin SMIRNOVA Svetlana SOLIMAN Dina S A STILGENBAUER Stephan TADMOR Tamar TOMIC Kristina TSE Eric VASSILAKOPOULOS Theodoros VISENTIN Andrea VITALE Candida VRACHIOLIAS George VUKOVIC Vojin WALEWSKA Renata XU Zhenshu YAGCI Munci YANEZ Lucrecia YASSIN Mohamed ZUCHNICKA Jana OSCIER David GOZZETTI Alessandro PANAGIOTIDIS Panagiotis BOSCH Francesc SPORTOLETTI Paolo ESPINET Blanca PANGALIS Gerassimos A POPOV Viola M MULLIGAN Stephen ANGELOPOULOU Maria DEMIRKAN Fatih PAPAJIK Tomas BIDERMAN Bella MURRU Roberta COSCIA Marta TAM Constantine CUNEO Antonio GAIDANO Gianluca CLAUS Rainer STAVROYIANNI Niki TRENTIN Livio ANTIC Darko SMOLEJ Lukas KALASHNIKOVA Olga B CATHERWOOD Mark SPACEK Martin POSPÍŠILOVÁ Šárka DOUBEK Michael NIKITIN Eugene CHATZIDIMITRIOU Anastasia GHIA Paolo STAMATOPOULOS Kostas

  Article in Periodical

  HemaSphere, year: 2024, volume: 8, edition: 9, DOI