prof. RNDr. Viktor Brabec, DrSc.

2008

• Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin

  KAŠPÁRKOVÁ Jana MARINI PALOMEQUE María Victoria BURSOVÁ Vendula BRABEC Viktor

  Article in Periodical

  Biophysical Journal, year: 2008, volume: 95, edition: 9

2006

• Structural Characterization, DNA Interactions, and Cytotoxicity of New Transplatin Analogues Containing One Aliphatic and One Planar Heterocyclic Amine Ligand

  RAMOS-LIMA Francisco J. VRÁNA Oldřich QUIROGA Adoración G. NAVARRO-RANNINGER Carmen HALÁMIKOVÁ Anna RYBNÍČKOVÁ Hana HEJMALOVÁ Lenka BRABEC Viktor

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2006, volume: 49, edition: 8

2005

• Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)]

  MARINI PALOMEQUE María Victoria CHRISTOFIS Petros NOVÁKOVÁ Olga KAŠPÁRKOVÁ Jana FARRELL Nicholas BRABEC Viktor

  Article in Periodical

  Nucleic Acids Research, year: 2005, volume: 33, edition: 18

• Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.

  NAJAJREH Yousef KAŠPÁRKOVÁ Jana MARINI PALOMEQUE María Victoria GIBSON Dan BRABEC Viktor

  Article in Periodical

  Journal of Biological Inorganic Chemistry, year: 2005, volume: 10, edition: 7

• Thermal stability and energetics of 15-mer DNA duplex interstrand crosslinked by trans-diamminedichloroplatinum(II)

  BRABEC Viktor HOFR Ctirad HOFR Ctirad

  Article in Periodical

  BIOPOLYMERS, year: 2005, volume: 77, edition: 4

2004

• DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.

  PROKOP Radim KAŠPÁRKOVÁ Jana NOVAKOVA Olga MARINI PALOMEQUE María Victoria PIZARRO Ana M. NAVARRO-RANNINGER Carmen BRABEC Viktor

  Article in Periodical

  Biochemical Pharmacology, year: 2004, volume: 67, edition: 6

2003

• Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action

  KAŠPÁRKOVÁ Jana NOVAKOVÁ Olga MARINI PALOMEQUE María Victoria NAJAJREH Yousef GIBSON Dan PEREZ Jose-Manuel BRABEC Viktor

  Article in Periodical

  Journal of Biological Chemistry, year: 2003, volume: 278, edition: 48

• DNA Binding Mode of the Cis and Trans Geometries of New Antitumor Nonclassical Platinum Complexes Containing Piperidine, Piperazine, or 4-Picoline Ligand in Cell-Free Media. Relations to Their Activity in Cancer Cell Lines

  KAŠPÁRKOVÁ Jana MARINI PALOMEQUE María Victoria NAJAJREH Yousef GIBSON Dan BRABEC Viktor

  Article in Periodical

  Biochemistry, year: 2003, volume: 42, edition: 20

2002

• A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464

  MCGREGOR Tracey D. HEGMANS Alexander KAŠPÁRKOVÁ Jana NEPLECHOVÁ Kamila NOVÁKOVÁ Olga PEŇÁZOVÁ Hana VRÁNA Oldřich BRABEC Viktor FARRELL Nicholas

  Article in Periodical

  Journal of Biological Inorganic Chemistry, year: 2002, volume: 2002, edition: 7

• Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium

  MARINI Victoria KAŠPÁRKOVÁ Jana NOVAKOVA Olga MONSU SCOLARO Luigi ROMEO Raffaello BRABEC Viktor

  Article in Periodical

  Journal of Biological Inorganic Chemistry, year: 2002, volume: 7, edition: 7