Mgr. Miroslav Vařecha, Ph.D.

Curriculum vitae

Person Identification

• Miroslav Varecha, Ph.D.
  Born on 28th November 1974 in Uherske Hradiste, Czechoslovakia, married, 1 child

Workplace

• Department of Biology,
  Faculty of Medicine, Masaryk University,
  Kamenice 5, Brno, 62500, Czech Republic.
  tel.: +420 549 496 696
  

Employment Position

• Research Scientist

Education and Academic Qualifications

• 2002 = Ph.D., Degree in Biophysics and Chemical Physics, Department of Experimental Physics,
  Palacky University, Olomouc, Czech Republic.
  Thesis: "Structural and functional characterization of uncoupling proteins UCP1, UCP2, and UCP3"
  
• 1998 = M.A., Degree in Biophysics and Chemical Physics, Department of Experimental Physics,
  Palacky University, Olomouc, Czech republic.
  Thesis: "Standardization of measurement of chlorophyl fluorescent spectra in leaf"

Employment Summary

• 2002-now = Research Scientist in Masaryk University.

Scientific and Research Activities

• Cell and Molecular Biology
  
• Bioenergetics
  
• Fluorescence microscopy and image analysis
  

Academical Stays

• 1998-2000 = Ph.D. Student Research Scholar, Supervisors: Professors K.D. Garlid and P. Paucek,
  Department of Biochemistry and Molecular Biology, Oregon Graduate Institute of Science and Technology,
  Beaverton, Oregon, United States of America.

Selected Publications

• GRABIEC, Marta, Hana HŘÍBKOVÁ, Miroslav VAŘECHA, Dana STŘÍTECKÁ, Aleš HAMPL, Petr DVOŘÁK a Yuh-Man SUN. Stage-specific roles of FGF2 signaling in human neural development. Stem Cell Research. Amsterdam: Elsevier Science BV, 2016, roč. 17, č. 2, s. 330-341. ISSN 1873-5061. Dostupné z: https://dx.doi.org/10.1016/j.scr.2016.08.012. info
• TAYLOR, S. Paige, Michaela BOSÁKOVÁ, Miroslav VAŘECHA, Lukáš BÁLEK, Tomáš BÁRTA, Lukáš TRANTÍREK, Iva JELÍNKOVÁ, Ivan DURAN, Iva VESELÁ, Kimberly N. FORLENZA, Jorge H. MARTIN, Aleš HAMPL, Michael BAMSHAD, Deborah NICKERSON, Margie L. JAWORSKI, Jieun SONG, Hyuk WAN KO, Daniel H. COHN, Deborah KRAKOW a Pavel KREJČÍ. An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome. Human Molecular Genetics. Oxford: Oxford University Press, 2016, roč. 25, č. 18, s. 3998-4011. ISSN 0964-6906. Dostupné z: https://dx.doi.org/10.1093/hmg/ddw240. info
• BUCHTOVÁ, marcela, Veronika ORALOVÁ, Anie AKLIAN, Jan MAŠEK, Iva VESELA, Zhufeng OUYANG, Tereza OBADALOVÁ, Žaneta KONEČNÁ, Tereza SPOUSTOVÁ, Tereza POSPÍŠILOVÁ, Petr MATULA, Miroslav VAŘECHA, Lukáš BÁLEK, Iva GUDERNOVÁ, Iva JELÍNKOVÁ, Ivan DURAN, Iveta ČERVENKOVÁ, Shunichi MURAKAMI, Alois KOZUBÍK, Petr DVOŘÁK, Vítězslav BRYJA a Pavel KREJČÍ. Fibroblast growth factor and canonical WNT/beta-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage. Biochimica et Biophysica Acta - Molecular Basis of Disease. Amsterdam: ELSEVIER SCIENCE BV, 2015, roč. 1852, č. 5, s. 839-850. ISSN 0925-4439. Dostupné z: https://dx.doi.org/10.1016/j.bbadis.2014.12.020. info
• VAŘECHA, Miroslav, Michaela POTĚŠILOVÁ, Pavel MATULA a Michal KOZUBEK. Endonuclease G interacts with histone H2B and DNA topoisomerase II alpha during apoptosis. Mol Cell Biochem. 2012, roč. 363, 1-2, s. 301-307. ISSN 0300-8177. Dostupné z: https://dx.doi.org/10.1007/s11010-011-1182-x. URL info
• VAŘECHA, Miroslav, Daniela PÁCLOVÁ, Jiřina PROCHÁZKOVÁ, Pavel MATULA, Dušan CMARKO a Michal KOZUBEK. Knockdown of apoptosis-inducing factor disrupts function of respiratory complex I. BIOCELL. Argentina: National Council of Scientific and Techn, 2012, roč. 36, č. 3, s. 121-126. ISSN 0327-9545. URL info
• UHLÍŘOVÁ, Radka, Andrea HARNIČAROVÁ, Gabriela GALIOVÁ, Soňa LEGARTOVÁ, Pavel MATULA, Miloslava FOJTOVÁ, Miroslav VAŘECHA, Jana AMRICHOVÁ, Jan VONDRÁČEK, Stanislav KOZUBEK a Eva BÁRTOVÁ. SUV39h- and A-type Lamin-Dependent Telomere Nuclear Rearrangement. Journal of Cellular Biochemistry. 2010, roč. 109, č. 5, s. 915-926. ISSN 0730-2312. Dostupné z: https://dx.doi.org/10.1002/jcb.22466. URL info
• VAŘECHA, Miroslav, Pavel MATULA a Michal KOZUBEK. Automated spinning disk confocal microscopy in 3D live cell imaging. In Mikroskopie 2010. 2010. info
• POTĚŠILOVÁ, Michaela, Miroslav VAŘECHA, Lenka TESAŘOVÁ a Irena KRONTORÁD KOUTNÁ. Time lapse living cells microscopy for studying CML: Preparation of Abl1- and Bcr/Abl - fluorescent protein vectors using Gateway technology. In Advances in Molecular and Cancer Biology, 2010. Brno: muni PRESS, 2010, s. 31-35. ISBN 978-80-210-5312-0. info
• VAŘECHA, Miroslav. AIFM2 (apoptosis-inducing factor, mitochondrion-associated, 2). Atlas of Genetics and Cytogenetics in Oncology and Haematology. Francie: INIST-CNRS, 2010, roč. 5, č. 14, s. 435-436. ISSN 1768-3262. Dostupné z: https://dx.doi.org/10.4267/2042/44747. URL info
• VAŘECHA, Miroslav, Michal ZIMMERMANN, Jana AMRICHOVÁ, Vladimír ULMAN, Pavel MATULA a Michal KOZUBEK. Prediction of localization and interactions of apoptotic proteins. Journal of Biomedical Science. BioMed website: BioMed Central, London, England, 2009, roč. 16, č. 59, s. 1-14. ISSN 1021-7770. info
• VAŘECHA, Miroslav, Daniela PÁCLOVÁ, Jiřina PROCHÁZKOVÁ, Pavel MATULA a Michal KOZUBEK. Prediction of localization and interactions of proteins involved in caspase-independent apoptosis. In Abstract Book of 17th ECDO Euroconference. 2009. info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Pavel MATULA a Michal KOZUBEK. Automated spinning disk confocal microscopy in 3D live cell imaging. In Funkční organizace buněčného jádra. 2009. info
• VAŘECHA, Miroslav, Vladimír ULMAN, Pavel MATULA a Michal KOZUBEK. Prediction of localization and interactions of apoptotic proteins. In Analytical Cytometry V. 2009. ISBN 978-80-254-2561-9. info
• ZIMMERMANN, Michal, Miroslav VAŘECHA, Jana AMRICHOVÁ, Vladimír ULMAN, Pavel MATULA a Michal KOZUBEK. Bioinformatic prediction, molecular modelling and image analysis of localization and interactions of apoptotic proteins endonuclease G, AIF, and AMID. In Apoptosis World 2008. 2008. URL info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Michal ZIMMERMANN, Vladimír ULMAN a Michal KOZUBEK. Image analysis of localization and translocation of apoptotic proteins in living cells. In European Light Microscopy Initiative. 2008. URL info
• VAŘECHA, Miroslav, Michal ZIMMERMANN, Jana AMRICHOVÁ, Vladimír ULMAN a Michal KOZUBEK. Interactions of apoptotic proteins AIF and endonuclease G analyzed by bioinformatic predictions, molecular docking, and fluorescent microscopy. In 16th Euroconference on Apoptosis an 5th Swiss Apoptosis Meeting. 2008. info
• VAŘECHA, Miroslav, Pavel MATULA a Michal KOZUBEK. New approaches to automated cell image acquisition and analysis using fluorescence microscopy. In XIX. Biologické Dny - International Symposium "The Functional Organization of the Cell Nucleus". 2008. ISBN 978-80-7399-545-4. info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Michal ZIMMERMANN, Vladimír ULMAN, Emilie LUKÁŠOVÁ a Michal KOZUBEK. Bioinformatic and image analyses of the cellular localization of the apoptotic proteins endonuclease G, AIF, and AMID during apoptosis in human cells. Apoptosis. USA: Springer Science, 2007, roč. 12, č. 7, s. 1155-1171. ISSN 1360-8185. info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Michal ZIMMERMANN, Vladimír ULMAN, Pavel MATULA a Michal KOZUBEK. Bioinformatic predictions and image analysis of localization and interactions of endonuclease G, AIF, and AMID in human cells. In Book of Abstracts for 15th Euroconference on Apoptosis. 2007. Stránka konference info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Michal ZIMMERMANN, Vladimír ULMAN, Marek KAŠÍK a Michal KOZUBEK. Fluorescent microscopy of living cells. In Analytical Cytometry IV: Book of Abstracts. 2007. ISBN 978-80-239-9591-6. info
• VAŘECHA, Miroslav, Jana AMRICHOVÁ, Michal ZIMMERMANN, Vladimír ULMAN, Emilie LUKÁŠOVÁ a Michal KOZUBEK. Bioinformatic and image analyses of cellular localization of apoptotic proteins endonuclease G, AIF, and AMID. In Symposium "Structure and Function of Cell Nucleus". 2007. info
• AMRICHOVÁ, Jana, Miroslav VAŘECHA, Daša MEDŘÍKOVÁ, Emilie LUKÁŠOVÁ, Jiří FAJKUS, Stanislav KOZUBEK a Michal KOZUBEK. Spatial Organization, Dynamics, and Associations of Telomeres in Healthy, Telomerase-Positive and ALT Human Cell Lines. In The Role of Telomeres and Telomerase in Cancer Research. 2007. info
• JEŽEK, Jan, Miroslav VAŘECHA, Jana AMRICHOVÁ, Michal KOZUBEK, Tomáš ČIŽMÁR a Pavel ZEMÁNEK. Optical tracking of microobjects within living cells. In Proceedings of SPIE. 6180. vyd. Bellingham, USA: International Society for Optical Engineering, 2006, s. 618025-1, 6 s. ISBN 0-8194-6236-5. info
• KOZUBEK, Michal, Petr MATULA, Pavel MATULA, Miroslav VAŘECHA, Jana AMRICHOVÁ, Vladan ONDŘEJ, Emilie LUKÁŠOVÁ a Stanislav KOZUBEK. Automated confocal in vivo microscopy based on spinning disks. In Focus on Microscopy: Program and Abstract Book. 2005. info
• JABŮREK, M., M. VAŘECHA, P. JEŽEK a K.D. GARLID. Alkylsulfonates as probes of uncoupling protein transport mechanism: ion pair transport demonstrates that H+ translocation by UCP1 is not necessary for uncoupling. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 2001, roč. 276, č. 34, s. 31897-31905. ISSN 0021-9258. info
• GARLID, K.D., M. JABŮREK, P. JEŽEK a M. VAŘECHA. How do uncoupling proteins uncouple? Biochimica et Biophysica Acta. Amsterdam: Elsevier Science B.V., 2000, roč. 1459, 2-3, s. 383-389. ISSN 0005-2728. info
• JABŮREK, M., M. VAŘECHA, R.E. GIMENO, M. DEMBSKI, P. JEŽEK, M. ZHANG, P. BURN, L.A. TARTAGLIA a K.D. GARLID. Transport function and regulation of mitochondrial uncoupling proteins 2 and 3. Journal of Biological Chemistry. Bethesda, USA: Amer. Soc. Biochem. Mol. Biol., 1999, roč. 274, č. 37, s. 26003-26007. ISSN 0021-9258. info

2017/03/14