Project information
Infertility due to chlamydia infection
- Project Identification
- NH7026
- Project Period
- 1/2002 - 12/2004
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- R&D of Gynaecology and Obstetrics
- MU Faculty or unit
-
Faculty of Medicine
- MUDr. Marcel Horký
- Keywords
- Chlam. trachomatis;immunology;reproduction;epidemiology;spermatology;serology;diagnostics
- Cooperating Organization
-
University Hospital Brno-Bohunice
- Responsible person doc. MUDr. Vít Unzeitig, CSc.
- Responsible person prof. MVDr. Zdeněk Věžník, DrSc.
Mapping of the prevalence of genital chlamydiosis in the Czech Republic. Detection of the presence of chlamydiae in the urogenital tract of 600 adolescents of both sexes, aged 16 to 20 years using noninvasive molecular biological techniques (PCR, LCR). Classification of findings in external and internal genitalia found in 300 gynaecological and 300 andrological patients positive for the presence of the infectious agent and antibodies to it. Demonstration of chlamydiae in sperm and anti-chlamydia and anti-sperm antibodies in serum and seminal plasma of the male patients. Demonstration of chlamydiae in genitalia and of antibodies to chlamydiae and HSP 60 in serum of infertile female patients. Analyses of longitudinal microbiological (chlamydia - disease), serological (anti-chlamydia antibodies - clinical manifestations), immunological (anti-sperm antibodies, heat shock protein- infertility), and spermatological indexes.
Publications
Total number of publications: 3
2004
-
Evidence of Antibodies against the Chlamydial Protein (cHSP60) in Women from in Vitro Fertilization Program
Česká gynekologie, year: 2004, volume: 69, edition: 4
-
Chlamydiae in the ejaculate: their influence on the quality and morphology of spem
Acta Obstetricia et Gynecologica Scandinavica, year: 2004, volume: 83, edition: 5
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Infekce Clamydophila pneumoniae jako příčina neplodnosti žen tubárního původu?
Česká gynekologie, year: 2004, volume: 69, edition: 5