Project information
Structural biophysics of macromolecules
- Project Identification
- GD204/03/H016
- Project Period
- 1/2003 - 12/2006
- Investor / Pogramme / Project type
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Czech Science Foundation
- Doctor grants
- MU Faculty or unit
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Faculty of Science
- prof. RNDr. Viktor Brabec, DrSc.
- prof. RNDr. Jaroslav Koča, DrSc.
- Keywords
- DNA, proteins, structure, cancer, antitumor drugs
The major objective of this project is to support, coordinate and make more effective scientific and research activities within the doctoral study program in the field of molecular biophysics and biology. Realization of this project will result incoordin ated activities within this doctoral study program of two research institutions in Brno with related and complementary scientific orientations in the fields of molecular biophysics and biology, namely the Faculty of Sciences of the MasarykUniversity - Na tional Center for Biomolecular Research and Institute of Biophysics, Academy of Sciences of the Czech Republic. A broader methodological orientation of the students participating in this project will be made possible by the use ofcomplementary and excell ent methodologies and instrumentation for research focused on the studies of structure of biomacromolecules and their interactions with the aid of the methods of molecular biophysics and biology.
Publications
Total number of publications: 40
2007
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Alternative entrances into the acetylcholinesterase active site
Year: 2007, type: Conference abstract
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Computational Studies on PA-IIL Lectin-Carbohydrate Interactions
Year: 2007, type: Conference abstract
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Conformational Dependence of 31P Chemical Shift Tensors in Nucleic Acids
Year: 2007, type: Conference abstract
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Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference
BMC Structural Biology, year: 2007, volume: 7, edition: 36
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Galectin-like protein from Ralstonia solanacearum
Current chemistry and biochemistry of saccharides - Cukrblik 2007, year: 2007
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Interesting behaviour of sugar-binding protein from phytopathogen Rasltonia solanacearum
Konference Grantové Agentury České republiky, year: 2007
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Mutagenesis of PA-IIL and related affinity changes - molecular modeling in service of protein engineering
Konference Grantové Agentury České republiky - Strukturní biofyzika makromolekul II., year: 2007
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Nahlédnutí do struktury a funkce lektinu RS20L z bakteriálního fytopatogenu Ralstonia solanacearum
Chem. Listy 101, 425–465 (2007) - VII. Mezioborové setkání mladých biologů, biochemiků a chemiků, year: 2007
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New approaches to structure and function studies of RS20L lectin from Ralstonia solanacearum
Materials Structure, vol. 14, no. 1 (2007), 6th Discussions in Structural Molecular Biology, year: 2007
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P-31 Chemical Shift Tensors in RNA and DNA Backbone. A DFT Study of Conformational Dependence and Its Implications for NMR Studies.
Year: 2007, type: Conference abstract