Project information
Spatio-temporal changes of cytokines in the dorsal root ganglia of experimental neuropathic pain models induced by unilateral nerve injury
- Project Identification
- GA309/07/0121
- Project Period
- 1/2007 - 12/2009
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- cytokines, chemokines, qualitative and quantitative changes
- Cooperating Organization
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St. Anne's University Hospital Brno
- Responsible person MUDr. Radim Jančálek,, Ph.D.
Peripheral nerve injury results in the peripheral neuropathic pain.
Publications
Total number of publications: 33
2009
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Bilateral elevation of IL-6, IL-6R, and gp130 mRNA and protein in the rat dorsal root ganglia after unilateral nerve constriction injury
Joint conference of the Czech and Slovak Neuroscience Societies, year: 2009
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Bilateral changes in IL-6 protein, but not in its receptor gp130, in rat dorsal root ganglia following sciatic nerve ligature
Cellular and Molecular Neurobiology, year: 2009, volume: 29, edition: 6-7
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Bilaterální elevace IL-10 v lumbálních a cervikálních gangliích po jednostranné ligatuře periferního nervu
Year: 2009, type: Conference abstract
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Experimental models of peripheral neuropathic pain based on traumatic nerve injuries. An anatomical perspective
Annals of Anatomy-Anatomischer Anzeiger, year: 2009, volume: 191, edition: 3
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Nové poznatky v patofyziologii zrcadlového typu bolesti
Year: 2009, type: Conference abstract
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Satellite glial cells synthesize IL-6 and express signal-transducing receptors to mediate IL-6 effect in the rat neuropathic pain model
Year: 2009, type: Conference abstract
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Vascular Alteration in the Dorsal Root Ganglia of Rat Neuropathic Pain Model
Year: 2009, type: Conference abstract
2008
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Bilateral elevation of pro-inflammatory cytokines (TNFa, IL-6) in the rat dorsal root ganglia following unilateral spinal nerve ligature.
Year: 2008, type: Conference abstract
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Corticosterone administration results in a significant decrease of IL6r and gp130, but not IL-6 protein in the rat dorsal root ganglia following sciatic nerve ligature
Year: 2008, type: Conference abstract
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Dynamika morfologických změn u experimentální komprese spinálních kořenů v korelaci s klinickou praxí
Year: 2008, type: Conference abstract