Project information
The influence of promising herbal antidepressant salidroside on drug metabolizing enzymes
- Project Identification
- MUNI/IGA/1261/2020
- Project Period
- 1/2021 - 12/2021
- Investor / Pogramme / Project type
-
Masaryk University
- Internal grant agency MU
- MU Faculty or unit
- Faculty of Medicine
Depression is a severe psychiatric disorder. Even though the patients can be cured with a variety of synthetic pharmaceuticals, only two-thirds of patients respond to such therapy. Traditional medicine can provide new active principles for the treatment of depression. Besides real therapeutic value, its potential for drug-drug interactions should also be evaluated. Our project aims to study the impact of promising herbal antidepressant salidroside on the most important drug metabolising enzymes.
Publications
Total number of publications: 4
2022
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In vivo and in vitro effects of salidroside on liver cytochrome P450
Year: 2022, type: Conference abstract
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The Effect of Salidroside on Liver Cytochrome P450
Year: 2022, type: Conference abstract
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Změna metabolické aktivity CYP1A2, CYP2A1 a CYP2C6 po subchronické aplikaci salidrosidu in vivo
Year: 2022, type: Conference abstract
2021
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Vliv salidrosidu na metabolickou aktivitu vybraných enzymů cytochromu P450 in vitro
Year: 2021, type: Conference abstract