Project information
The impact of derivation substrate on differentiation of human embryonic stem cells for the cell therapy
- Project Identification
- MUNI/IGA/1332/2021
- Project Period
- 1/2022 - 12/2022
- Investor / Pogramme / Project type
-
Masaryk University
- Internal grant agency MU
- MU Faculty or unit
- Faculty of Medicine
Human embryonic stem cells (hESC) are able to differentiate into every cell type in the human body (e.g., neural, cardiac, or retinal cells), which may then be the basis for cell therapies. Our aim is to examine how substrate used for derivation of hESC influences their differentiation propensity, which is critical for the potential application of hESC in a clinical setting. Here, we study the capacity of hESC derived on different substrates to produce cells of all three embryonal lineages.
Publications
Total number of publications: 3
2024
-
Truncated vitronectin with e-cadherin enables the xeno-free derivation ofhuman embryonic stem cells
Year: 2024, type: Appeared in Conference without Proceedings
2023
-
Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells
Scientific Reports, year: 2023, volume: 13, edition: 1, DOI
-
Vitronectin is a xeno-free and defined surface for the derivation of human embryonic stem cells
Year: 2023, type: Conference abstract