Project information
Use of monoclonal immunoglobulin for preparation of antitumor vaccine in patients with multiple myeloma
- Project Identification
- NC6763
- Project Period
- 1/2001 - 1/2003
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- R&D of Oncology
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
-
University Hospital Brno-Bohunice
- Responsible person prof. MUDr. Roman Hájek, CSc.
Isolation of Id protein from plasmapheresis product of patients with MM is possible in sufficient amount for repeated vaccination Imunomagnetic separetion is used to prepared myeloma cell suspension from bone marrow aspirate with more than 75% of myeloma cells for preparation of TAA from myeloma cells lysate
Publications
Total number of publications: 3
2004
-
Využití monoklonálního imunoglobulinu k přípravě protinádorové vakcíny u nemocných s mnohočetným myelomem - První zkušenosti z klinické studie.
Klinická onkologie, year: 2004, volume: 17, edition: 2
2002
-
Isolation of monoclonal immunoglobulin from plasma of patients with multople myeloma using affinity chromatography
Zborník XVII.Biochemický zjazd, year: 2002
-
Příprava a použití nádorového antigenu z patologického imunoglobulinu pro pacienty s mnohočetným myelomem.
Transfúze a hematologie dnes, year: 2002, volume: ročník 8, edition: 3